Immunology Of Hbv Study Among People In Xinjiang Reproduction And Construction Corps

Objective:To understand the present stage of the Xinjiang Production and Construction Corps, the situation of hepatitis B vaccine, hepatitis B serological status and influencing factors, and control of hepatitis B Corps to improve inoculation efficiency, provide the basis for promoting quality services.Methods:(1) using stratified cluster sampling method 8 Mission Field:44 groups,49 groups,52 groups, 53 groups,143 groups,145 groups,147 groups,152 groups, self-designed questionnaire, in which 8 a mission field in the three companies were randomly selected, respectively, in 12 age groups:8 months of age,8 months to 2 years～3 years～,～5 years,7 years old～,10～,15～,20～,25～,30～,35 years old were randomly selected in proportion to the survey, questionnaires were (children instead of reply by the guardian). The questionnaire included:demographic data, hepatitis B-related knowledge, immunization history. (2) survey is completed, each survey 3ml blood collected, blood samples were collected in 1420 were effective. Blood samples collected on the use of ELISA to detect surface antigen, surface antibody. (3) statistical package using SPSS 13.0, using Chi-square test, non-conditional logistic regression analysis to calculate relative risk (OR) and 95% confidence interval.Results:(1) Hepatitis B vaccination rate factors:nationality, the OR value:0.167 (95.0% CI:0.100-0.280); group, the OR value:0.449 (95.0% CI:0.212-0.953); hepatitis B on the knowledge of reference of 0 to 3 were divided into groups,4 to 6 hours,7 to 9 into comparison group, the OR values were:253.316 (95.0% CI:59.505-1078.382),53.207 (95.0% CI:12.407-228.174). (2) the general situation of immune serum:serum samples in 1420, the hepatitis B HBsAg, HBsAb positive rates were:3.2%,59.4%, and the standardized rate of HBsAg positive, and the standardized HBsAb positive rates were 5.17%,57.81%; In the 884 serum samples of children, hepatitis B HBsAg, HBsAb positive rate:1.6%,60.1%, and the standardized rate of HBsAg positive, and the standardized HBsAb positive rate:2.34%,55.79%. Of which 451 were children under 4 years of age and serum samples, HBV HBsAg, HBsAb positive rates were:0.4%, 66.5%, and the standardized rate of HBsAg positive, HBsAb positive rates were standardized as follows: 0.50%,66.07%. (3) HBsAg-positive rate:children less than adults (X2=19.107, P=0.000<0.05),6 years of age and children under 7 to 15 year-old children (X2=4.678, P=0.031), the floating population and permanent population the difference was not statistically significant (X2=0.537, P=0.464> 0.05), higher than the northern South(X2=8.958, P=0.003), males than females (X2=4.882, P=0.027). (4) HBsAb positive rate of factors:people, the OR value:5.544 (95.0% CI:1.977-15.551); dose, the OR value:0.248 (95.0% CI:0.053-1.151); vaccination program, its OR value:4.564 (95.0% CI:1.880-11.080); hepatitis B on the knowledge of reference from 0 to 3 were divided into groups,4 to 6 hours,7 to 9 into comparison group, the OR values were:0.023 (95.0% CI:0.005-0.104),0.090 (95.0% CI:0.031-0.260); immunization injections, as compared to needle inoculation group 1,2 or more needles, needle times for the comparison group is not clear, the OR values were:9.551 (95.0% CI:0.554-164.668),17.211 (95.0% CI:1.316-225.069). Conclusion:1. Hepatitis B vaccination rates:Han higher than minority children than adults, hepatitis B on the knowledge of good than poor people.2. Corps of hepatitis B prevention and control at the national level is good. However, HBsAb positive rate of children from the national average there are still gaps. HBsAg positive rate:adults than children,7 to 15 year-old children and children above 6 years of age, men than women, higher than the northern South; HBsAb positive rate:higher than the Han ethnic minorities,10ug of inoculation doses higher than 5ug, "0,1,6" standard vaccination procedures than other vaccination, knowledge about the situation (children instead of reply by the guardian) good than poor people, vaccination injections also have an impact on the positive rate of HBsAb.