| Purpose:To provide some theoretic basis for early clinical diagnostics of MCI and prevention and intervention of AD,it learned about memory impairment characteristics of mild cognitive impaiment,and what related to TCM syndroms.Method:From May in 2009 to January in 2010,we have surveyed the data of 114 Retired olders in chengdu geriatric hospital between 60 and 90 years old,and screened 45 MCI patients, including 26 males and 19 females,and 31cognitive-normal persons,which are 22 males and 9 females.All of them accepted questionnaire survey and neuropsychology evaluation,and informed consent. Finally,combined the data of medical history with the results of neuropsychology, we should make a diagnosis.Rusult:There are 45 MCI patients and 31 normal cognitive persons,which have attended in statistical analysis.â‘ The characteristic of memory impairment of MCI mainly aspected on memory, language, attention, direction, calculation and so on.In MCI group,the scores of directive memory, learning by association,free recall,meaningles phase portrait characteristics and memory quotient were significantly reduced after normal cognitive group.(all P<0.01).â‘¡In MCI patients, the syndrom of deficiency of the kidney and marrow is 42.2%,and the syndrom of turbid phlegm obstructing brain is 24.4%,and the syndrom of qi-stagnation and blood stasis is 22.2%.The scores of MCI patients of deficiency-excess mixing syndrome are obviously higher than which of deficiency syndrome.However,there are no evident differences between deficiency-excess mixing syndrome and deficiency syndrome in CMS scores,MQ and MMSE scores(P>0.05).â‘¢Moderately negative correlation is existed in the scores of MQ,MMSE scores and TCM differentiation all P<0.01).Conclusion:There is certain relevence between TCM syndroms and memory impairment characteristics of amnestic mild cognitive impaiment,which can offer some objective evidence to TCM differentiation of mild cognitive impairment. |
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