Bisphenol A Migration Characteristics In The Nanochannel

Nanochannel is the pores or tubules with diameter from 0.1 to 100 nm. Nanochannel technique is exhibiting great advantage in the fields of chemistry, material science, biomedicine and life sciences due to its size effect, specific surface area effect, and particular physicochemical characteristics.It has been found that many industrial chemicals dispersed in the environment have adverse effects on the endocrine systems in humans and animals. Among the tens of endocrine disrupting chemicals (EDCs) identified so far, alkylphenols (including 4-nonylphenol and 4-t-octylphenol), bisphenol A and 2,4-dichlorophenol are often studied as a group of phenolic environmental estrogens due to their structural and estrogenic similarities. Among these estrogens, bisphenol A is widely used as the raw material to produce polycarbonate and epoxy resin in our country, so it is essential to develop sensitive, convenient and selective methods for the phenolic environmental estrogens. Hereby, main works in the present thesis are shown as follows:1 Au was deposited within the pores of the polycarbonate template membrane with an electroless deposition method and gold nanotubes with controlled diameters were obtained. Ultraviolet spectroscopy, scanning electron microscope, transmission electron microscope were used to characterize the pore size and the surface appearance. Au nanotubes with high reproducibility and controlled diameters were successfully prepared by optimizing the factors affecting deposition process,. 2 Chloride ion and L-cysteine were self-assembly modified onto the inner wall of Au nanotubues, respectively, and the electroosmotic flow (EOF) within the nanotubules was investigated in the presence of electric field. The strength and direction of electroosmotic flow (EOF) can be controlled by controlling the current flux and direction across the membrane. Modification of L-cysteine in the nanotubules and the change of the solution pH can alter the surface charge of the nanotubules, resulting in the change of EOF.  The effects of surface properties of the nanotubules on electroosmotic flow were studied.3 The Au nanotube membranes were modified with hydrophobic lauryl mercaptan (HSC12H25) and hydrophobic p-aminothiophenol (PATP) to change the properties of the membrane surface. The effects ofβ-cyclodextrin on the transportion property of bisphenol A across the hydrophilic or hydrophobic membrane were studied.