Clinical Study On Treatment Of Cancer - Induced Fatigue Of Lung - Kidney Yin Deficiency By

Objective Observing the clinical effects and the safety of the Gold-Water FuYuan prescription when treating cancer-related fatigue with the lung and kidney yin deficiency by studying the patients with cancer-related fatigue.Methods 66 patients metting the inclusion criteria selected from the department of oncology in wangjing hospital were randomly divided into two groups(test group and control group) according to the proportion of 1:1.Patients in the control group were treated with basic symptomatic treatment, the test group received the treatment with basic symptomatic treatment and the Gold-Water FuYuan prescription invented by my mentor (the prescription consists of rehmannia 30g, angelica 15g, poria lOg, ginger pinellia 9g, tangerine peel 10g, licorice 10g, coke divine comedy 10g, coke malt 10g, coke hawthorn 10g).The treatment cycle was 14 days. The observing indicators of the clinical effects were the TCM symptom scores、the revised piper fatigue scales、KPS scales, and the observing indicators of the safety were blood rt, liver and kidney function, electrocardiogram.Results Study subjects were included 66 patients in each group completed a clinical trial in which 30 cases. Before starting treatment, the two groups of patients were gender composition, age distribution, types of cancer, body weight, functional status score (KPS score), symptom scores, Piper Fatigue Scale total score and fatigue behavior, emotional fatigue, fatigue perception fatigue and cognitive areas such as statistical analysis, P> 0.05, grouping established, can be studied. In both groups before and after treatment symptom score as efficacy evaluation criteria, the treatment group,30 cases effective rate 96.66%, control group of 30 patients with efficiency 23.33%, P<0.01, the difference was statistically significant. Were compared before and after treatment Fatigue Scale score, fatigue score behavior, emotional fatigue score, fatigue score perception and cognitive fatigue scores, the differences were statistically significant (P<0.05), fatigue scale scores were compared, behavior fatigue score, fatigue score emotional, perceptual and cognitive fatigue fatigue score score difference before and after treatment (before treatment-after treatment), the difference was statistically significant (P<0.05). Comparison of the therapeutic group KPS scores before and after treatment, the difference was not statistically significant (P> 0.05), the difference in the control group KPS scores before and after treatment groups was not statistically significant (P> 0.05), after treatment between the two groups KPS scores the difference was not statistically significant (P> 0.05), described Goldwater recovery parties before and after the patients in this study had no effect on treatment KPS score. The treatment group Treatment group differences in weight before and after there was statistically significant (P <0.01), weight control group before and after treatment in the group, the difference was statistically significant (P<0.05), two groups of patients after treatment, the difference between the body Reorganization statistically significant (P> 0.05), the difference between the two groups of patients before and after treatment weight (after treatment-before treatment), the difference was statistically significant (P<0.05). Two subjects safety indexes before and after treatment comparison group, the difference was not statistically significant (P> 0.05) in the group.Conclusions The Gold-Water FuYuan prescription could improve the symptoms of fatigue effectively of the patients with cancer-related fatigue of the lung and kidney yin deficiency, and make the life quality of cancer patients better, this prescription is safe and effective, worthy of promotion.