Analysis Of Correlation Factors Of Slow Coronary Flow

Objective: To analyze the correlation factors of slow coronary flow retrospectively. Metheds: The study population included 186 patients with angiographically proven normal coronary a rteries admitted during August 2005 to December 2008. Coronary flow patterns of the cases were determined by Thrombolysis in Myocardial Infarction (TIMI) method. Patients who belonged to TIMI 2 or lower than it were included in the slow coronary flow group (n=96) and the others were included in the control group (n=90). Results: There was no statistical difference between the two groups in respect to age, gender, history of hypertension, diabetesmellitus, cigarette smoking, alcohol using, platelet count, hemoglobin level, fasting plasma glucose, triglyce ride, total cholesterol and LDL-cholesterol level (P>0.05). However, body mass index, hemaocrit, white blood cell were significantly higher in the slow coronary flow group compared with the control group (27.06±3.40 kg /m2 vs 25.53±3.57 kg /m2, P<0.05; 0.43±0.07 L/L vs 0.41±0.04 L/L, P<0.05; 6.65±1.73×109/L vs 6.05±1.56×109/L, P<0.05; respectively), But HDL-cholesterol level were significantly lower than the control group (1.12±0.28 mmo l /L vs 1.21±0.26 mmo l /L, P<0.05). Logistic regression test sugest that, body mass index, white blood cell were the risk factors of slow coronary flow (OR 1.373, 95% CI 1.146~1.645, P=0.001; OR 1.920, 95% CI 1.234~2.987, P=0.004; respectively). Conclusions: Reduce in HDL-cholesterol level and increase in hemaocrit may paly a role in the pathogenesis of slow coronary flow. And body mass index, white blood cell may be the risk factors of slow coronary flow.