| Objective: To study frying principles of Foeniculum vulgare Mill. and offered theory for frying mechanism research and different samples of Fried Foeniculum vulgare Mill. selection in clinic. Methods: (1) Cleaned F. Vulgare were fried with nothing, salt solution, vinegar, wine and ginger juice, honey, Pharbitis nil, salt solution, vinegar, wine and bran, respectively, according to different Chinese medicine frying theories. (2) Different volatile ingredints were extracted from fried products, and their contents and physical constants were detected. Gas chromatography-mass spectrometry (GC-MS) was developed for analyzing the changes of effective ingredients in Foeniculum vulgare Mill after been fried. The sorts and contents of elements in different samples of Fried Foeniculum vulgare Mill. were scaned and analysed by using Spectroscopy. (3) To assay hemorheology by blood acute blood stasis model. Results: (1) To observe different samples of Fried Foeniculum vulgare Mill. (2) The content and physical constants of volatile oil in Foeniculum vulgare Mill changed after been fried. Among all fried samples, trans-anethole had the maximum content, furthermore, cis-sabinenehydrate, cis-ocimene, alpha-terpinene, 4-terpin-en, p-allyianisole and cuminal were detected for the first time in Foeniculum vulgare Mill. The contents and kinds of the twenty-four compounds changed a lot. Thirty-second elements were found in Foeniculum vulgare Mill. and it was firstly found that the content of Hg rose greatly in Foeniculum vulgare Mill. stir-fried with nothing. (3) Among all samples, the effects of F. vulgare Mill. fried with honey on hemorheology was best. Conclusion: (1) Different fried samples of F. vulgare Mill. has effects on the contents and physical constants and ingredients of volatile, elements, hemorheology, which showed it was right for different samples of Fried Foeniculum vulgare Mill. selection in clinic. (2) The effects of F. vulgare Mill. fried with honey on hemodynamics was the best. |
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