| Objective:Collection of type 2 diabetes and diabetic peripheral neuropathy in Chinese dialectical sub-type related to the clinical laboratory tests, the study of type 2 diabetes and diabetic peripheral neuropathy related risk factors, provide a theoretical basis for clinical research and direction.Methods:Collection of 2007 to 2009, Wuhan, the first hospital diagnosed type 2 diabetes patients and a total of 100 normal group of 30; and the type 2 diabetes patients are in line with WHO in 1999, published by the IDF diabetes diagnosis standards; and the type 2 diabetes around diabetes neuropathy 100 cases of patients (DPN) in the dialectical Yam virtual hot Sheng, gas Yam two empty, Yin and Yang two virtual 4 group category, and to the laboratory testing indicators; blood glucose sugar oxidase measured by law; insulin measuring the use of chemical luminous, blood fat measured by the law; insulin sensitivity index empty stomach, blood sugar and an empty stomach, insulin product in the last of HOMA-IS=20×FINS/(FBG-3.5); nerve physical inspection (according to clinical symptoms are measured in the total nerve nerve, protect the nerve conduction movement and the speed, nerve foot decay nerve, intestinal nerve sensory nerve conduction rate); all data for measuring X S±0. (±0. of standard deviation), A t tests; the Information Counter X 2 tests; the Ridit level information analysis.Results:l.DPN group after dialectic according to the Yin deficient internal heat, was mad that cloudy two empty, the masculine and feminine elements two empty three groups carry on the classification, the card are complex, is mad the cloudy two empty majorities in the dialectical minute, the course later period many by the masculine and feminine elements two empty primarily.2. DPN TCM syndrome types of various degree of order of IR yin and yang deficiency type "Qi and Yin Deficiency type" hot-Sheng Yin Deficiency type; the certificate course with the Yin-type hot-Sheng Group, Qi and Yin Deficiency group, yin and yang deficiency group and gradually extended, there are significant differences; TG higher than the normal control group, HDL Yin and Yang deficiency group declined significantly (P<0.05); DPN concurrent chronic disease in Chinese medicine distribution of various syndromes of yin and yang deficiency with Qi and Yin Deficiency group and the highest group, significantly higher than the hot-Sheng Yin group (P <0.05);3. Diabetes neuropathy around the card, FINS FBG type, HOMA-IR, HOMA-IS measured the permit more visible in Chinese medicine with FBG Yam virtual hot shing group, gas, Yin Yin and Yang two virtual group two virtual group of blood, gas on securities group are rising, the Group more differences between 22 significant (OP.05); Yin and Yang two virtual group of blood and Gas Group has significantly on gas Yam two less than a virtual group, Yam virtual hot Sheng Group (P<0.01); Yin and Yang two virtual group of blood and Gas Group differences on no significant (>OP.05); Yin and Yang two virtual Group and the other group HOMA-IR, HOMA-IS compared with the findings suggest gas Yam two virtual group HOMA-IR value other high (P<0.05), and HOMA-IS low compared with other group (P<0.05), Prompt insulin resistance [1] Island and I beta cells secretion DPN functional decline in the incidence of the role of the first, diabetes neuropathy around the card type HbA 1 c, measured H b A1 c more visible level with virtual Yin Sheng Hot Air, Yin Yin and Yang, the two empty, false evidence on gas chambers in turn increase blood,22 more differences between group marked (<0.01 P);4. Diabetic peripheral neuropathy the nerve conduction velocity syndrome comparison of the various TCM syndromes seen DPN nerve conduction velocity showed nerve damage to Yin Deficiency and Heat set to light; both Qi and Yin deficiency group were of no significant (P> 0.05); yin and yang, and qi stagnation and blood group differences between groups was not significant (P> 0.05); of yin and yang Yin Deficiency and Heat group had significantly lower (P<0.05), statistically significant; gas lag Yin Deficiency and Heat Blood group had significantly lower (P<0.05), statistically significantConelusion:1.IR, lipid metabolism disorder in the DPN of the occurrence and development have an important significance;2.DPN TCM syndromes reflect the pathophysiological changes in different stages, among which the most common Qi and Yin deficiency, Yin and Yang Deficiency and Blood context card for end-stage performance;3.Insulin secretion index (HOMA-IS) group with Yin Deficiency and Heat, Qi and Yin deficiency group, yin and yang deficiency, blood stasis and vein were respectively lower order; insulin resistance index (HOMA-IR) was then decreased trends; tips HOMA-IS and HOMA-IR in DPN by Traditional Chinese Medicine Syndromes of the variation.4.High uric acid can cause inflammation-related factors in microvascular disease, resulting in peripheral nerve damage; uric acid related to gender, male patients than female patients with uric acid. |
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