Clinical Research Of Breast Cancer Treatments By Yiqi Yangxue Shugan Decotion Assisting TE Chemotherapy

Purpose:To observe the efficacy and safety of breast cancer treatments by Yiqi Yangxue Shugan Decotion assisting TE (Epirubicin and Docetaxel) chemotherapy, so as to evaluate the status of TCM applied in adjuvant chemotherapy of breast cancer and provide a reliable basis for clinical application.Methods:40 cases of postoperative breast cancer patients are randomly divided into the treatment group and the control group by Random Number Table. 20 cases in the treatment group are treated by Yiqi Yangxue Shugan Decotion combined with TE; 20 cases in the control group are simply treated by TE.TCM symptoms, KPS scores, QOL by FACT-B, solid tumor sizes, serum tumor markers (CEA, CA153, CA125) and the toxic side effects are compared before and after the treatments between the groups.Results:Between the groups there's no statistical significance in the change of solid tumor sizes as well as the tumor markers (CEA, CA153, CA125) (P>0.05).The efficacy of TCM symptoms, KPS scores are statistically significant (P<0.05).In the FACT-B scale, the Physical Well-beings, Emotional Well-beings and Additional Concerns are statistically significant (P<0.05), and there's significantly statistical difference in FACT-B summary (P<0.01). In terms of security, leukopenia and anemia differences are significant (P<0.05).Conclusion:Yiqi Yangxue Shugan Decotion can improve common symptoms and QOL and mitigate marrow suppressions for postoperative chemotherapy patients with breast cancer, which is worth promotion and further study.