| Objective:The study which was carried through animal experiment evaluated the ability, feature and differences in guiding new bony tissue regeneration of two bony substitutional material inorganic-derived and bio-derived bone in their reparation of bony defects.Methods:Filled the bony defect areas in 18 rabbits' calvarium with inorganic-derived or bio-derived bone meal and then cover with collagen membrane. The repairing situation is observed and analysed by X-ray, HE and Masson's trichrome staining on the bone tissue slices at 12,16 and 24 weeks after the operation.Results:Both of inorganic-derived and bio-derived bone meal have biocompatibility, the ability to guid bony tissue regeneration and the possibility to operate in the process of repairing rabbits' calvarium defects.Conclusion:Both of inorganic-derived and bio-derived bone meal can both guid bony tissue regeneration and completely cover the calvarium defects. And, the bio-derived is better. |
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