The Relationship Between Peripheral Arterial Pressure And Central Aortic Pressure Among Hypertensive And Non-hypertensive People

Objective This topic aims at exploring the peripheral arterial pressure and central aortic pressure situations of the hypertensive patients and non-hypertensive group, to identify the relationship between peripheral arterial pressure and central aortic pressure as well as whether there is relationship difference in hypertensive patients and non-hypertension population. Method In 97 routine left heart catheterization patients, composing of hypertensive and non-hypertensive group; use the catheter to directly measure the aortic reflection wave increased pressure in the central arterial (AP), aortic output pressure (PI), central aortic diastolic pressure (CDP), the time of central arterial wave starting to the start of reflection wave (IT), calculate artery pulse pressure (PP=AP+PI), central aortic systolic pressure (CSP= PP+CDP), reflection wave augmentation index (AI= AP/PP; meanwhile, use mercury sphygmomanometer with a cuff to measure the right upper arm brachial artery pressure. Results 1. Generally speaking,54 males and 43 females with the average age of 57.7±13.3, compared with non-hypertensive group, there is no statistic significance of hypertensive plasma smoking and high-density lipoprotein cholesterol. Other factors such as age, body mass index, blood sugar, uric acid, cholesterol, triglycerides and LDL cholesterol have significant differences (P<0.01).2. The brachial artery systolic pressure of all research objects measured by cuff method is significantly higher than the ascending aortic systolic pressure measured by catheter method, P< 0.001, while there is no significant difference compared with the diastolic blood pressure and the average pressure is statistically significant (P< 0.05). However, the different value of the diastolic pressure of the two groups has no statistical significance.4. The pulse pressure difference gradually narrows along with increasing age, while the absolute value of pulse pressure increases.5. The pulse pressure difference gradually increases in different ages. With increasing age, the reflected wave pressure increases, the pressure increasing index ratio increases and the starting time of reflection wave advances. There is significant different after the age of 50 (P< 0.01 on average).Conclusions The brachial systolic pressure measured by cuff method can not fully represent central aortic systolic pressure. However, after the grouping of the research objects, there is a more significant difference between non-hypertensive group and relatively high blood pressure group; with increasing age, the PP gas is in narrowing trend, indicating the different value between ascending aortic pressure and brachial artery systolic pressure is in positive correlation with the ascending aortic pulse pressure, further proving the inconsistency is decided by the atherosclerosis. The central aortic PP increase is a strong predicting factor for cardiovascular, while brachial artery pressure can not entirely replace the role of CAP.