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The Distribution Of Saikosaponin D In Mice

Posted on:2011-10-15Degree:MasterType:Thesis
Country:ChinaCandidate:G Q PengFull Text:PDF
GTID:2154360305489340Subject:Biochemistry and Molecular Biology
Abstract/Summary:PDF Full Text Request
The Saikosaponin D is belong to epoxy ether type pentacyclic triterpenoids homogeneous type fruit alkyl derivatives. Chno: C42H68O13, Mw: 780.96. There are many reports of pharmacological actions on Saikosaponin D. It has Pharmacological activity of antiendotoxin and Anti-tumor.It is very important natural compounds.I detect blood and tissue of mice with HPLC.Method: I collect blood and tissue of mice after 0.5 hours, 1 hours, 2 hours, 4 hours and 6 hours. I collect Saikosaponin D with HPLC after treated plasma and tissue samples. The Saikosaponin D distribute in plasma and tissue after injecting. It is more higher than Other hours in 2 hours. Then It is fall away. It is best high in 2 hours. It is more high in the tissue. It is different in the tissue. The Saikosaponin D is very active. It saves in blood and tissue With Other forms in many hours.
Keywords/Search Tags:Saikosaponin D, Intraperitoneal, Injection Tissue, distribution, HPLC
PDF Full Text Request
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