Objective: On the basis of the literature study, a deep and comprehensive exploration to the connotation of the collateral theory was performed, and its role in oculopathy, especially in Diabetic Retinopathy (DR) was illustrated. Under the guidance of the collateral theory, the clinical efficacy of DR was observed, which may provide a theoretical guidance and a clue to the clinical work in dealing with DR.Methods: 41 patients with DR are divided into test group(n=21) and control group(n=20) randomly. The test group was treated with modified ShengMaiyin combined with DAHUANGZHECONG PILL and Acupuncturing, while the Control group was treated based on syndrome differentiation and treatment. After 60 days, the items (symptoms,vision,signs of fundus,Blood Lipid,Blood Rheology)were compared to those before the treatment. Results: The clinical study showed that①the modified ShengMaiyin with DAHUANGZHECONG PILL and Acupuncturing can improve the ocular symptoms obviously and the efficiency is better than control group(P<0.05)②vision is improved,and the effection is better than the control group(P<0.05)③the absorption of blooding and exudation of retinopathy is done much better than the control group(P<0.05)④Blood Lipid is decreased much better than the control group(P<0.05)⑤Blood Rheology is decreased uncommonly. There is significant difference between the test group and the control group.(P<0.01)Conclusion: Modified Sheng Maiyin combined with DAHUANGZHECONG PILL and Acupuncturing had good therapeutic efficacy in DR,its excellent rate is 38.1℅.Its effective rate is52.4℅. The total effective rate is 90.5℅. Its efficacy is much better than control group 50℅(P<0.01).Conclusion: Treating DR under the guidance of the Collateral Theory, could effectively improve the clinical eye symptoms,vision, faciling the absorption of blooding and exudation of the eye infectous focus, descend Blood Lipid,Blood Rheology. The method of supplementing qi and nourishing yin,dissipating phlegm and removing blood stasis,detoxicating and diacollaterals can prevent and cure DR effectively. So it is worthy of further researching.
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