Yi Qi Yang Xin Granules On Chronic Systolic Heart Failure Clinical Research

Background Chronic systolic heart failure (chronic heart failure) is systolic dysfunction, cardiac output so that the absolute or relative below the metabolic needs of the syndrome in general organization, is the heart failure of the more common type. Chronic heart failure is the ultimate destination of most cardiovascular diseases, has become one of the main causes of death, therefore, study of chronic heart failure has become the focus of cardiovascular research, and by the general medical sector highly valued. In recent years, the development of chronic heart failure in the mechanisms and therapy have made considerable progress, but the disease remains a threat to people's health and life potential killer. Confirmed by extensive research of Chinese medicine in the treatment of chronic heart failure has its unique advantages, with a stable effect, improve the quality of life of patients. Instructor Professor Yang Baoyuan proposed that "Power of heart qi " and "Pulse smooth ", and held that the "Heart qi deficiency " and "Vascular obstruction " is two basic factors of the changes in heart function occurred, and eventually lead to heart failure. "Insufficient yang Heart " and " Vascular obstruction " is the basic pathogenesis.With the method of "yiqiwenyang, huoxuetongmai" for treating heart failurein clinical, useing own Yi Qi Yang Xin Granules and treating TCM is" qi (yang) deficiency and blood stasis "of chronic heart failure patients achieved good clinical efficacy.Objective(s) The subject of design through observation in the form of clinical cases, use the Yi Qi Yang Xin granules and observe clinical efficacy, based on the treatment of chronic systolic heart failure in clinical practice in patients.And while with the conventional treatment of chronic systolic heart failure drug treatment compared, then investigates chronic systolic heart failure in the medical treatment. Thus summarized as "insufficient yang Heart" and " Vascular obstruction " as the basic pathology in patients with chronic systolic heart failure, treatment in Chinese medicine with " yiqiwenyang, huoxuetongmai " as to chronic contraction of the basic treatment of heart failure provide the basis for Chinese medicine, as the basis for new drug development. Methods Based on the target, since March 2008 - December 2 009 years, were selected 80 cases in Cardiology ward Tangshan Chinese medicine hospitals met the inclusion criteria of chronic systolic heart failure outpatients and inpatients, according to two groups in age, gender, primary disease and the degree of heart failure have comparable requirements of various options, 40 cases were divided into treatment group and control group of 40 patients, using clinical observations recorded in the form of a table. Treatment group in the conventional therapy to Yi Qi Yang Xin Granules (teacher experience side) from Tangshan Chinese medicine hospital preparation room by the national standard preparation into granules. 2 bags each (20g), 3 times a day, warm water. 3 months to one assessment of treatment. Control group, treatment with conventional Western medicine, plus placebo (preparations of cardiac agent appearance and, like Yi Qi Yang Xin), each 2 bags (20g), 3 times a day, warm water. 3 months for a course evaluation. After treatment of the two groups using statistical analysis techniques for statistical analysis.Result(s) 1. After treatment, the degree of heart failure points, cardiac function, 6-minute walk test, left ventricular ejection fraction improved than before treatment, between the two groups are significantly different, P <0.05, treatment group than the control group.2. After treatment, Chinese medicine clinical symptom scores were lower, TCM clinical syndrome has significantly improved compared with before treatment, P <0.05; group had significant difference, P <0.05, treatment group than the control group. Traditional Chinese medicine symptoms of comparison, total effective rate was 87.5%, control group was 72.5%, significantly different, the treatment group than the control group. 3. Before and after treatment on quality of life were significantly different, and the quality of life after treatment in both groups also had a significant effect, P <0.05, treatment group was significantly better than the control group.Conclusion(s) 1. Yiqi yangxin granule in 40 cases treatment of chronic systolic heart failure patients with clinically effective effect.2.To heart yang deficiency and the clinical, myocardial contraction and weak pulse Road, bleeding, blood reduced compliance of the basic pathogenesis of chronic systolic heart failure patients, treatment should be based on Wenbuyangqi, power and improve myocardial and Huoxuetongmai, enhance blood flow to conform to the basic method. Useing of Yi Qi Yang Xin Granules instructors owned, to yiqiwenyang, huoxuetongmai to cure patients with chronic systolic heart failure is quite effective, then the teacher many years experience in treatment of heart failure based on the "Power of heart qi " and "Pulse smooth "to support the view.