Physiological Functions Of Pancreas And Stomach After Binding Pancreaticojejunostromy Or Binding Pancreaticogastrostomy

Objective:Through a prospective randomized research, we record the related biochemical parameters of pancreas and stomach after Binding Pancreaticogastrostomy or Binding Pancreaticojejunostomy, to discuss the physiological function's changes of pancreas and stomach after two different anastomose.Methods:In this prospective randomized clinical research,25 cases who underwent pancreaticoduodenectomy were recruited from general surgery department of SirRunRunShaw hospital between November 2009 and March 2011.All the patient are randomized divide into two treatment group, Binding Pancreaticogasrostomy (BPG) group and Binding Pancreaticojejunostomy (BPJ) group. To analyze the physiological effect of these two anastomosis, some important biochemical parameters of blood and gastric liquid, were measured pre-and post-operation.Results:15 patients underwent Binding Pancreaticogasrostomy (BPG) and 10 patients underwent BPJ after their pancreatic operation. The two treatment groups were comparable in multiple parameters, including medical history, demographics, preoperative laboratory values, and operative time, blood transfusions, pancreatic texture etc; while, the anastomosis time of BPG group was significant shorter than that of BPJ group (36.0±10.2 vs.52.5±16.6 minutes) (p< 0.05); there were no significant difference in biochemical parameters of blood, gastric between the two groups; Moreover, and not existing significant difference in postoperative anus exhaust time, taking off gastric tube time, feeding time, and weight change of the two groups.Conclusion:BPG is a operation as convenient as BPJ. BPG is a safe and physiological anastomosis, and could be highly recommended in clinical application.