The Epidemiological Status And Risk Factors Survey Of Hypertensive Disorder Complicating Pregnancy Among Some District In Changsha

Objectives:To comprehend the epidemiological status of hypertensive disorder complicating pregnancy (HDCP) among some district in Changsha through retrospective analysis, to explore relationships between HDCP and related factors, and to screen risk factors from the related factors, and to provide epidemiological evidences for HDCP early intervention.Methods:During July to August in 2010,2148 cases-histories recorded between 2008 and 2009 were acquired from Department of Maternal and Child Health Institute among some district in Changsha. First, the incidence of HDCP in that region was statisticed, and the distinguish between the HDCP and the normal at age, labor gestational weeks and fetus birth weight was comprehended by x2 test; followed by univariate uncondition logistic regression analysis with HDCP as a dependent variable, independent variables internalized including age, body mass index (BMI) before pregnancy, mean arterial pressure (MAP) of mid-gestation, history of preeclampsia, and history of diabetes or kidney disease; finally the related factors were evaluated by multivariate uncondition logistic regression analysis.Results:1. Obeserved regions had a 5.21% HDCP incidence rate during 2008 to 2009; gestational hypertension account for 75.0%, mild preeclampsia account for 17.9%, severe preeclampsia account for 5.3% and chronic hypertension concurrent preeclampsia account for 1.8%.2. The incidence of eld gravidas, prematurity and low birth weight was higher of the HDCP than the normal (P<0.01).3. Univariate uncondition logistic regression analysis showed:(1) Age, BMI before pregnancy, MAP of mid-gestation, history of preeclampsia, and history of diabetes or kidney disease were related with HDCP;(2) Gravidity, parity, the numbers of abortion and multiple gestation pregnancy have no significant correlation with HDCP.4. Multivariate uncondition logistic regression analysis showed:(1) Age:eld gravidas (age>35years) have more possibility with HDCP (OR= 5.871,95%CI:2.650～13.008);(2) BMI before pregnancy:overweight or obesity before pregnancy increased relative risk of HDCP (OR=2.291,95%CI:1.682～3.121);(3) MAP of mid-gestation:the higher of MAP of mid-gestation, the higher of risk of HDCP (OR=45.719,95%CI:15.616～133.854);(4) History of preeclampsia:gravidas with history of preeclampsia have more possibility with HDCP(OR=12.387,95%CI:2.676～57.337);(5) History of diabetes or kidney disease:gravidas with history of hypertension or diabetes or kidney disease have more possibility with HDCP(OR=22.338,95%CI:5.581～89.413).Conclusions:1. HDCP incidence is 5.21% in the observed region of Changsha during 2008 to 2009;2. The incidence of eld gravidas, prematurity and low birth weight was higher of the HDCP than the normal;3. Age, BMI before pregnancy, MAP of mid-gestation, history of preeclampsia, and history of diabetes or kidney disease were risk factors for HDCP.