Advanced Effect Of PRF To Soft And Hard Tissues In Immediate Implant And Immediate-loading Implant

ObjectiveThrough the establishment of animal model of immediate implant immediate loading implant, to observe the growth of soft and hard tissue with platelet-rich fibrin.MethodsThe bilateral mandible 4th premolar (PM4) of 5 beagle dogs was extracted. Immediately the implant surgery was operated. Left and right side of each animal mandible were implanted one titanium cylindrical screw threaded implant respectively. The implant superstructure was installed after implant surgery immediately in order to ensure immediate loading. Self-controlled design was applied in experiment. Experimental side was filled PRF in the buccal of implant, the interval defect and the tooth extraction socket, the buccal defect implant filler do not fill any filler, interval bone not prepared defect, tooth socket was filled with gelatin sponge. the second day after planting day the healing of soft tissue was observed; the planting day and 3 months after surgery, X-periapical films ware taken to observe the new bone around implant; 3 months after, the location and formation of new bone was observed, and measured and recorded. At the same time, bilateral buccal bone of implants, the interval bone and extraction socket bone were cut, and HE sections were made and observed under the light microscope.ResultsAfter planting, the observation of the average of soft tissue healing time were 5.80±0.84 days in the experimental group,8.20±0.45 days in the control group. Three months after planting, experimental X-ray films shows images denser than the control group. The average increased height of the buccal bone was 2.60±1.19mm in the experimental group, 1.60±1.52mm in the control side;the average increased buccal defect area was 1.45±1.46 mm2 in the experimental group,3.00±2.15 mm2 in the control side. Light microscopy of bone sections shows that the osteoblasts in the buccal of implant in experimental group more than in the control group; the maturity of osteoblasts in the interval bone was similar to the control group; the osteoblasts in the tooth extraction socket in experimental group more than in the control group.ConclusionImmediate implant immediate loading of implants with PRF, will promote the healing of soft tissue, reduce the healing time of soft tissue, promote the preservation of alveolar bone with new bone formation, promote the osseointegration.