| On the basis of Review of fatigue, This subject research and developed a health food——The Compound Morinda officinalis How Chewable TabletsThe Compound Morinda officinalis How Chewable Tablets is anantifatigue health food, which is made of Morinda officinalis How, Rhodiola crenulata (Hook. f. et. Thoms.)H. Ohba and Panax quinquefolium L. In order to make The Compound Rhodiola crenulata (Hook. f. et. Thoms.) H. Ohba Chewable Tablets register a legal produet, we must study its preparation teclmology quality standard and pharmacodynamic according to health food registration regulation of Ministry of Public Health.According to the physical and chemical properties of the effective ingredients in the medicinal materials, With the content of Salidroside in the extract solution and extract yield as the indices, the optimum extracting condition for Rhodiola crenulata (Hook. f. et. Thoms.) H. Ohba and Morinda officinalis How was selected by using orthogonal design. With the Taset and preparation moulding as the indices, the optimum formulation of The Compound Morinda officinalis How Chewable Tablets was screened. Preparation processes was based on pilot production, the results show that the process route was reasonable and stable. Quality standard of The Compound Morinda officinalis How Chewable Tablets was studied. We chose Salidroside as the index and established HPLC methodology to control the quality of preparation. The Morinda officinalis How, Rhodiola crenulata (Hook. f. et. Thoms.)H. Ohba and Panax quinquefolium L were identified with TLC.Preliminary evaluation of pharmacodynamic. All of which provide evidences are to register production and studying its pharmacodynamics. |