Professor He Shidong Dissertation Topic: The Persistent Nephritic Syndrome Treatment Experience

1, BackgroundRefractory nephritic syndrome (RNS) refers to special primary nephritic syndrome that is invalid to hormone therapy or depends on it or with repeated attacks. The clinical manifestations of patients with complex cause the delay of refractory, which makes it become one of the most difficult problems of nephrology. In recent years, with Chinese medicine research and clinical application, to some extend, integrated traditional Chinese treatment together with RNS could reduce hormone side effects and enhance curative effect. What's more, it reduces the recurrence as well. And many studies show that integrated traditional Chinese with RNS seems better than therapeutic method of pure western medicine therapy.Our country has a large number of famous old herbalist doctors, and their clinical experience is the sublimation of ancient medicine theoretical basis and development, representing the highest level in the contemporary Chinese academic medicine development. The clinical experience of famous old herbalist doctor has been one of the most urgent needs for research currently.2, Research PurposeTo summarize and inherit the academic experience that Professor He Shidong has been maintained about the treatment of RNS.3, Research ContentThe article is mainly divided into three parts. Based on the motherland medicine and modern medicine the first part focuses on the modern Chinese medicine of RNS clinical characteristics, difficult factors for the cure of disease, the factors, the etiology and pathogenesis, therapeutic principle, alopecia, etc. The second part systematically summarizes professor's treatment of RNS etiology and pathogenesis, syndrome to ideology, diagnosis and treatment, drug characteristics and cultivate guide and so on. The third part makes deep and comprehensive exploration of his experience with the help of frequency statistics, inductive, analysis and other methods.4, Research ResultsThis research altogether collected medical records, including 57 cases and 364 diagnosis times.The important internal cause of RNS is because of the long illness, while the external cause accounts for the criterion with damp pathogen, heat pathogen, wind pathogen, engorgement.The most common former 10 symptoms; lacking in strength, spiritlessness, aching lumbus and knees, dizziness, dreamful, hand and foot had lost the temperature, hydropic face and foot, pharyngitis, spumy urine, limb burnout; The most common tongue qualitative light pulse:dark or reddish, tongue, or see big fat body have teeth marks, coating on the edge of thin, white, greasy, looked like heavy fine slippery.Judging from the statistics of location and pathogenesis, the RNS is about deficiency in origin (yang deficiency of spleen and kidney) and excess in superficislity (wind-evil,damp evil,heat evil,blood stasis). Use frequency in more than 50 times with 13 kinds of therapies, nourishing yin, supplementing qi, clearing damp and promoting diuresis, invigorating the spleen are used most frequently. It reflects Professor H's principle-to strengthen body resistance and eliminating evil. RNS in different stages of pathogenesis, edema period of the notifying kidney and spleen and clearing damp and promoting diuresisis crucial, while in non-edema period the tonify kidney Qi Yin, clearing heat and dampness is crucial.From the research,162 kinds of herbs are used in 4386 drug times.. The top ten frequently used herbs are Fuling, yam, Cornus, Atractylodes, Ligustrum lucidum, astragalus, Alisma, Rehmannia, Gorgon, Coix seed. From the medicinal odour, the majority of medicines are qi-restoratives medicine. From the staging, in the edema period of RNS, the top three commonly used drugs are the Astragalus, Poria, and Alisma, while for non edema period, are yams, Rehmannia, and Poria.5, ConclusionProfessor He considered the pathogenesis of RNS is asthenia in origin (insufficiency both in the spleen and the kindey)and asthenia in superficiality (wind-evil,damp evil,heat evil,blood stasis). The nature of pathogenesis base on eficiency-excess complication, and remaining of pathogens due to deficiency of vital QI.Dialectically divide into different stages is crucial in treatment. On edema period, edema elimination for urgent, and insufficiency of both the spleen and the kindey, insufficiency of the spleen with overabundance of dampness, impairment of defensive QI due to wind are the main 3 kinds. n clinical medicine, professor He emphasised on strengthen body resistance by the way of invigorating spleen and kidney, while to eliminating evil by the way of eliminating damp,reducing heat and removing blood stasis, and also concern with guidance of patients in health education.