The Clinical Significance And Morphologic Study Of Marrow Hematophagocytes In Adult Hemophagocytic Syndrome

Objective: To investigate the morphology of marrow hematophago- cytes by a retrospective analysis of the marrow smears in 20 cases with hemophagocytic syndrome(HPS) and probe its clinical significance.Methods: The 20 cases were divided into maturity group and infant group by the morphology of the marrow hematophagocytes. the clinical symptoms, signs, laboratory examinations and the mortality rates were compared between the two groups.Results: Compared with the characteristics of the infant group, the age of the maturity group was significantly older(P<0.05); the level of platelet and albumin were significantly lower(P<0.05) and the mortality rate was significantly higher(P<0.05).Conclusions: The morphology of marrow hematophagocytes is an important prognostic factor in HPS. HPS patients in the maturity group have a more serious bleeding tendency and hypoimmunity, so have a much higher risk of uncontrollable hemorrhage, infection, multiple organ dysfunction syndrome(MODS) and death, and should be paid more attention in clinical.