Influencing Factors Relative To Lymphatic Matastasis Of T2 Rectal Carcinoma

ZHUANG Jin-fu , YE Jian-xin , HUANG Yong-jian , ZHENG Wei , CHEN Shaoqin.Department of gastrointestinal surgery,The first affiliated hospital of fujian medical university,Fuzhou,350004,China [Abstract] Objective:To study the influencing factors relative to lymphatic matastasis of T2 rectal carcinoma,and choose the appropriate T2 rectal carcinoma for local resection.Methods:Consecutive cases of 122 patients with T2 stage rectal cancer with radical surgery in the first affiliated hospital of fujian medical university from 2006 to 2011 were included for retorspective analysis . Clinical and pathological characeristics,including age,gender,tumor site,tumor size,tumor circumferential extent,morphological type,CEA level, histological type,lymphovascular invasion,tumor differentiation and depth of invasion were assessed.Results:The rate of lymph node metastasis was 21.3%(26/122) ;and the rate of lymph node metastasis was 13%(7/54) in shallow muscularis group,and 28%(19/68) in deep muscularis group.tumor site,morphological type,histological type,tumor differentiation and depth of invasion were risk factors for lymph node metastasis according to univariate analysis . Significant predictors of lymph node metastasis in both univariate and multivariate analysis was depth of invasion.Conclusion:The depth of invasion is important risk factor for lymph node metastasis in T2 rectal carcinoma.