| ObjectiveIn this study, oral medicine through Penyan and progesterone pill health sequential therapy mixture with combined laparoscopy surgery for H-HSP60 antibodies in patients with salpingitis infertility, testing patients before and after three menstrual cycle serum heat shock Protein 60 antibody IgG and tumor necrosis factor, observed the levels before and after treatment of Chinese medicine on serum IgG antibody heat shock protein 60 and tumor necrosis factor, as well as the impact on pregnancy rate of patients, investigate the nature of traditional Chinese medicine on non-salpingitis Pregnancy after laparoscopy surgery in patients with HSP-60 antibodies, TNF-a concentrations in patients with intrauterine pregnancy rate and the impact.Method1. Choose from June 2009 to November 2010 received treatment in Traditional Chinese Medicine First Affiliated Hospital of Gynecology Ward salpingitis infertility, were in the menstrual clean anesthesia 3-7 days after laparoscopic surgery, surgery before fasting blood sample, HSP-60 antibodies were measured, TNF-a levels. According to the situation in pelvic surgery, salpingitis infertility in full compliance with the standard case is included in 40 cases. In accordance with the randomized, controlled the principle of grouping, A group of experimental group (Yan Kang+progesterone pill) in 21 cases, B group (control group tubal+progesterone pill) in 19 cases.2. All patients were discharged from hospital 7 days after surgery, A group of patients is the next menstrual cramps, Yan Kang mixture to give continuous basin proprietary oral 14 dayseach 25ml,3 times a day, taking three consecutive menstrual cycles as a course. B group were the next 3-7 days after menstrual clean line of tubal surgery, medication, or 0.9% saline 20ml+gentamicin 80000 U+dexamethasone 5mg+αchymotrypsin 4000U, liquid flow three consecutive menstrual cycles a course of treatment. Two groups of patients during treatment in each menstrual cycle,10 B-day monitoring of follicular development and ovulation, every other day, were monitored 3-4 times, guiding conception.3. Both groups were in the treatment of three menstrual cycles, not pregnancy, in the first four months of 3-7 days after menstrual cycle clean, blood, determination of patient serum HSP-60 antibody in vivo, TNF-a levels. If A, B groups during the treatment of pregnancy, the termination of treatment programs instead of tocolysis therapy, diagnosis of early pregnancy in the next day fasting blood investigations HSP-60 antibodies, TNF-αlevels. Both groups were followed up for 6 months after operation. The two groups were recorded intrauterine pregnancy, ectopic pregnancy situationResults1.Oral inflammatory kang mixture experimental with basin HSP60 antibody IgG,TNF alpha, preoperative and postoperative drop concentration degree with a statistical significance (P<0.05)2. Control liquid groups of patients the HSP60 antibody IgG, TNF alpha concentration preoperative and postoperative decline degree was statistically significant(P>0.05).3. Group A group of 21 cases,13 cases of pregnancy, pregnancy rate for 61.9%。Group B group of 19 cases,10 cases of pregnancy, pregnancy rate for 52.6%。the total pregnancy rate of A, B groups was 57.5%.4. Group A group of 21 cases,8 cases of intrauterine pregnancy, intrauterine pregnancy rate for38.1%。Group B group of 19 cases,4cases of intrauterine pregnancy, intrauterine pregnancy rate for21.1%。5. A, B postoperative intrauterine pregnancy, ectopic pregnancy rate was not significant (P>0.05)。6. With the HSP-60 antibody serum IgG concentration increased, the tubal patency rate decreased, tubal obstruction rates increased. Proportional relationship between the two.7. Along with the serum HSP-60 antibody IgG concentration increases, tubal lesion site of fallopian tube from umbrella end adhesion around, deformation, YuQu tubal obstruction, out-of-the-way, to increase gradually, the illness.Conclusions 1.Hong mixture Penyan can reduce salpingitis infertility the serum HSP-60 antibody, NHF-αconcentration, balance and improve immune function.2. laparoscopy surgery in patients with oral hong mixture Penyan and treatment of tubal, can improve the postoperative pregnancy rate.3. Yan Kang mixture can improve the basin pelvic inflammation, and promote functional recovery of the oviduct, salpingitis infertility patients to improve the intrauterine pregnancy rate.4. The highe concentration of IgG antibodies in serum HSP-60, the more severe tubal obstruction. Serum HSP-60 antibody concentration and tubal lesion site, and positively related illness degree than.5. Salpingitis infertility patients whether intrauterine pregnancy, tubal damage not only to the extent of patients, the serum HSP-60 antibodies, TNF-αlevels, but also with pelvic adhesions situations. |
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