Clincal Evaluation Of Hydroxyethyl Starch On Aute Cerebral Infarction

Objectives:Cerebrovascular disease is a common and frequently-occurring disease in the elderly. The disease brings the society and the patient's family heavy burden in terms of sprit and economy . Cerebral infarction hazards human's health seriously, and usually leaves some sequelae after treatment.The disease affects the quality of life of patients. The causes , mechanism and factors of acute cerebral infarction has become a major topic to research for the scholars all over the world. The study would provide an important basis for the treatment and prognosis to the patients with ischemic cerebrovascular disease . In recent years ,there are a large number of domestic and foreign studies on the treatment of acute cerebral infarction.But there is little report on the hydroxyethyl starch and its relationship with the prognosis. This research is focus on utilizing hydroxyethyl starch to treat acute cerebral infarction and evaluating the prognosis of the disease. This research provode a basis to the therapy and judging the prognosis of acute cerebral infarction.Methods:The 100 patients diagnosed with acute cerebral infarction who are informed, divided into control group and treatment group randomly, 50 patients in each group.The patiens in the both of the two groups are parallel in gender, age, history, the interval time from the onset to the initial treatment , neurological starting points, the lesion distribution and extent similar. The patients in treatment group were supplied supportive treatment, brain cell protection, prevention of infection and hydroxyethyl starch 500 ml, ivd , 1-5 days. The patients in control group were only supplied conventional drug treatment.,but without Hydroxyethyl starch. Before the treatment ,1 week and 2 weeks assessing NIHSS score and CSS score. It is divided into basic cure rate improvement, significant progress, progress, no change,.and calculating the total effective according to the former 3 indexs .Measured the blood glucose, blood lipids, liver function, kidney function, blood coagulation routine before and after treatment. Monitoring of blood pressure and heart rate.Result:(1) Blood glucose, blood lipids, liver function, kidney function showed no significant difference before and after treatment. Blood pressure, heart rate did not change significantly.(2) During the first week of there are differences between the two groups,which has nothing to do with before.The second week there are significant differences between the two groups.Scores after treatment than before treatment groups decreased significantly, but the treatment group improved more significantly than the control group.(3) Treatment group markedly effective rate was 86%, the effective rate was 94%; control group markedly effective rate was 70%, the effective rate of 86%.Conclusions:(1) Hydroxyethyl starch has high security and it hasn't significant effect on the cardiovascular system, liver and kidney.(2) Hydroxyethyl starch has little effect on blood pressure.(3) Hydroxyethyl starch can improve the symptoms, physical sign apparentely. It could alleviate the symptons of the patients who are troubled with acute cerebral infrction earlier.