The Effect Of Intraaortic Ballon Pumping (IABP) On Slow Coronary Flow Phenomenon In Emergency Percutaneous Coronary Intervention

ObjectiveTo investigate the effect of Intra-aortic balloon pumping (IABP) on slowcoronary flow phenomenon(SCF) in emergency Percutaneous coronary intervention(PCI) for ST elevation Myocardial Infarction(STEMI).MethodsClinical data of 30 ST elevation myocardial infarction patients after PCI with angiographic slow coronary flow phenomenon were retrospectively analyz-ed between January 2006 and December 2008.15 patients were performed IABP. other 15 patients as control group.Observe several neuroendocrine fact-ors including plasma renin activity (PRA), angiotensinâ…¡(ANGâ…¡), aldosterone (ALD),norepinephrine (NE) and epinephrine (E) as well as Cardiac injury markers including Myoglobin (MYO), creatine kinase isoenzyme (CK-MB), troponin I (CTNI). In both groups on the days of 1,2,3,5,7,10 after the different interventions. In order to evaluate the left cardiac structure and cardiac ventricle systolic function between two groups, and Finally, statistics was token to analysis the data.ResultsPatients of the two groups were successfully implanted stent. All the neuroendocrine factors have no difference between the two groups before operation. The neuroendocrine factors declined rapidly after PCI according to the curve. PRA,ANGâ…¡,ALD,NE and E of IABP group were significantly lower than control group(P<0.05)at the first or second day after IABP; But the peak of IABP group is ahead of control group. MYO,CK-MB and CTNI have no difference between the two groups before operation, but IABP group declined rapidly, the peak of CTNI IABP group is ahead of control group. There was a positive correlation between neuroendocrine and cardiac injury markers. 10d 3 months,6 months of left cardiac structure and 10d,3 months of LVEF have no difference(P>0.05), but LVEF of IABP group is significant difference control group after 6 months(P<0.05).ConclusionsDeteriorated neuroendocrine and Cardiac injury markers change were significantly improved with IABP, which brought forward the peak of CTNI, Obviously raised LVEF of 6 month, relieved damage for myocardium and implied potential benefits on heart function, IABP had effects on AMI patients who perform PCI with angiographic slow coronary flow phenomenon.