Optimization Of Models Of Mechanical Virtual Human Of China And Its Applicaion In Oral Medical Field

Due to the variability, diversity of human musculoskeletal system and limitation of experiment condition in vivo, it is very difficult to do the research on mechanical property for human. At the same time, different surgery method occurs with the improvement of medical condition, now it becomes much more important to do the research on how to choose the best method and to evaluate the postoperative effect.This dissertation is based on the key project ?Mechanical Virtual Human of China', which is supported by National Natural Science Foundation, and a project cooperated with Shanghai 9th People's Hospital.The main contents can be included in:1) The geometrical model of thoracolumbar spine was established based on image data of frozen section, then the 3D finite element model including cortical bone, cancellous bone and posterior of vertebra, endplate, annulus fibrosis and nucleus pulposus of lumbar intervertebral disc In order to extract the outline of the bone and muscle as possible as precision, which optimized the database of Mechanical Virtual Human of China.2) The part of L3-L4 functional elements was took as the example to discuss the principle in modeling finite element models. The comparation of five different finite element model with different element size was made, and the conclusion will be useful in modeling other models of human beings in biomechanics.3) The geometrical and finite element models of cranio-maxillofacial complex musculoskeletal system, which includs bones, teeth, periodontal ligament, mucosa and masticatory muscles. Then the software of Mechanical Virtual Human of China was developed based on the models, which improved the head module. 4) The models was used in the stomatology——reconstruction of distal-extension missing. By comparing the results of five different removable partial dentures, the evaluations was got, which provide a theoretical support for the chosen of denture kinds and benefit patients.The geometrical and finite element models of human thoracolumbar spine and cranio-maxillofacial complex musculoskeletal system were established, which can be widely used in human biomechanical analysis, such as the biomechanical evaluation of dentures in repairing and reconstructing, and thus to guide the design of dentures.