Research On Chinese Materia Medicine Using Law In Coronary Heart Disease With Acute Coronary Syndrome

Objective:Investigate Chinese material medical using in coronary heart disease with acute coronary syndrome (ACS), through research the hospitalized patients'information, and apply statistical analysis on their Chinese medicine syndromes and Chinese material medical use.Methods:Develop data collection forms, including basic data, the basic symptoms of Chinese medicine, diagnosis, symptoms style and prescriptions based on the research purpose, then entry the cases all original data met inclusion criteria into computer, after a database establishment under the software Excel 2003 support, statistical analysis, finally conclude the rules of Chinese material medical using in ACS.Results:1. The general laws:herbs categories from highest to lowest were, blood activating medicine, qi supplement, phlegm transformation, heat clearing, qi regulation, dispel dampness and yin nourish medicine; commonly used traditional Chinese medicine were danshen root, red peony root, sichuan lovage root, saffron, rosewood, prepared pinellia tuber, Licorice root, glabrous greenbrier rhizome, haire holly root, scutellaria hypericifolia and snakegourd fruit.2. The syndrome style laws:Blood stasis syndrome:danshen root, red peony root, rosewood, saffron and walnut. Qi deficiency syndrome:licorice root, milk-vetch root, codonopsis, white atractylodes rhizome, heterophylly false satarwort root and Radix Astragali. Phlegm turbid syndrome:prepared pinellia tuber, snakegourd fruit, babon shavings, bile arisaema, platycodon root and thunderg fritillary buld. Heat toxin syndrome:haire holly root, scutellaria hypericifolia, figwort flower, rehmannia root, tree peony bark and figwort root.Qi stagnation syndrome:aged tangerine peel, immature organ fruit, organ fruit, long stamen onion bulb, pummelo peel and nutgrass galingale rhizome. Yin deficiency syndrome:wart lilyturf tuber, dendronbium, towbrack landpick, four leaf ladybell root, lily buld and fragrant solomonseal rhizome. Yang deficiency syndrome:eucommia bark, morinda root, sharp leaf glangal fruit, Himalayan teasel root and aerial part of epimedium herb. Cold condense syndrome:cassia twig and dried ginger rhizome。3. Common chinese medicines syndromes and herbs, are followed:phlegm obstruction in hart meridian and hart blood obstruction:danshen root, red peony root, rosewood, saffron, sichuan lovage root, prepared pinellia tuber, licorice root, snakegourd fruit and glabrous greenbrier rhizome, haire holly root, scutellaria hypericifolia and aged tangerine peel.Qi deficiency and blood stasis:danshen root, red peony root, rosewood, saffron, sichuan lovage root, rosewood, walnut, licorice root, scutellaria hypericifolia, glabrous greenbrier rhizome, prepared pinellia tuber and milk-vetch root. Qi and yin deficiency, heart blood stasis:danshen root, milk-vetch root, red peony root, sichuan lovage root, rosewood, saffron, wart lilyturf tuber, Chinese magnoliavine fruit and licorice root. Qi deficiency and blood stasis, heart meridian obstruction:danshen root, licorice root, prepared pinellia tuber, sichuan lovage root, saffron, red peony root, rosewood, glabrous greenbrier rhizome and aged tangerine peel. Phlegm obstruction in heart meridian:danshen root, red peony root, saffron, glabrous greenbrier rhizome, sichuan lovage root and prepared pinellia tuber. Qi stagnation and blood stasis:danshen root, red peony root, saffron, glabrous greenbrier rhizome, sichuan lovage root, rosewood, licorice root and scutellaria hypericifolia. Heat congestion and blood stasis:rosewood, saffron, danshen root, red peony root, sichuan lovage root, haire holly root, scutellaria hypericifolia and figwort flower. Phlegm obstruction in heart meridian, heat congestion and blood stasis:red peony root, sichuan lovage root, prepared pinellia tuber, danshen root, saffron, licorice root, rosewood, glabrous greenbrier rhizome, haire holly root, walnut, snakegourd fruit and rehmannia root. Yang qi deficiency, heart blood stasis: danshen root, licorice root, rosewood, codonopsis, saffron, glabrous greenbrier rhizome, milk-vetch root, sichuan lovage root and red peony root.4. Related factors analysis:according to Western medicine classification analysis, using qi supplement and blood activating herbs with high frequency in unstable angina (UA), while blood activating and phlegm transformation herbs always used in non-ST segment elevation myocardial infarction (NSTEMI) and ST segment elevation myocardial infarction (STEMI). Base on sex Analysis, phlegm transformation and heat clearing herbs were likely used in male patients, in addition to blood activating herbs; while we paid more attention to qi tonic in women patients. According to age, we applied by heat clearing and qi regulation herbs below age of 65 years are more frequently than that over the age, because we emphasized on qi supplement at that age. Patients those who with thrombolysis or PCI, heat clearing or blood activating herbs ware frequently used, and those without thrombolysis or PCI were managed with blood activating and qi supplement herbs. Given risk factors:whether there is associated diseases (hypertension, diabetes, dyslipidemia or not, mainly used blood activating herbs, under compared hypertension and diabetes patients and those without these three disease, the frequency of qi regulation herbs in hypertension and diabetes group is much higher than those without the three with disease; and compare dyslipidemia group and that without these three disease, qi regulation and phlegm transformation herbs using with higher frequency. By period analysis:the frequency of heat cleaning herbs use has greatly enhance after 2007,96.73% of patients met the inclusion criteria under medicine injection treatment, and 72.55% using the proprietary Chinese medicines.Conclusion:Depend on Clinical Case Summary of ACS, we know that the majority of patients were used blood activation herbs in gernaral, which meet the major syndromes in ACS is heart blood stasis according to the modern scholars report; followed by qi supplement and phlegm transformation herbs, those are in line with the majority patients were the South elderly; besides the frequency of hot herbs use has greatly improved after 2007, because toxic heat syndrome factor in ACS is further understood. The included patients, the use of Chinese medicine injection rate is 96.73% 72.55% is use of oral proprietary Chinese medicines, The application of proprietary Chinese medicines, Chinese medicine treatment on behalf of the current hot spot and the main trends in ACS, not only reflects a part of traditional Chinese medicine effective identification and preparation process of continuous improvement, making Chinese medicine can play a fast, efficient, conforming with Chinese "radical is to govern themarked "principle.