Research Differential Treatment Rules Of Knee Osteoarthritis

Objective:To investigate the Traditional Chinese Medicine (TCM) differential treatment rules of knee osteoarthritis. Improving the theoretical understanding of knee osteoarthritis in TCM, Thus directing clinicians to elect prescription and use drugs. In order to provide new ideas and methods for researching osteoarthritis by TCM.Method:To collect and sort out the pathogenesis, syndrome, therapy and prescription in which the bi syndrome of joint in various types of Chinese literatures and case records from the ages(including the Warring states period to the Qing dynasty), to establish the database systems. Using the mathematical statistics and analysis statistical methods to analyze and summarize the treatments and prescriptions of the bi syndrome of joint in literatures. Reasoning out differential treatment rules of knee osteoarthritis with TCM by the summary of law of the bi syndrome.Results:1. Medications rules1.1 Frequency analysisTonic medicine, rheumatism medicine, relieving medicine, traditional medicine, resolving dampness medicine, medicine Qi, warming medicine, antipyretic medicine such as 8 drugs cumulative frequency up to 88.6% in the prescriptions of treating the bi syndrome of joint. Tonic medicine, rheumatism medicine, relieving medicine, traditional medicine, resolving dampness medicine, medicine Qi such as 6 drugs cumulative frequency up to 78.3%. These are the main drug prescription constituting the treatment of the bi syndrome of joint and playing a major role in clinical. The hot drugs are used frequency up to 52.1% in ancient treatment of the bi syndrome of joint from the choice of cold or hot drugs. 1.2 Cluster analysisVarious types of drugs are the goal of stable and can not be divided to gather up to seven categories. The results of these seven categories are reasonable with clinical expertise. Bidentata, cinnamon, peony, monkshood, wind, Chuan xiong, licorice and angelica are the main treatment drugs of the bi syndrome of joint in ancient physicians.1.3 Factor analysisF1 is composed of the warming medicine and wetting drug diuresis, revealing the pathomechanisms are changed by cold and dampness causing. Wetting drug applications have the coup of leading the water wet out by urine. Is the so-called wet treatment is not the correct treatment method if negative urine. F2 and F4 are composed of the warming medicine and divergent cold medicine, revealing the pathomechanisms are changed by wind,cold and dampness causing. F3 is composed of the divergent cold medicine and traditional medicine, revealing the pathomechanisms are changed by the pathogenic factors of lags, gas coagulation shibuya. Emphasising on activating blood is before expelling wind, wind is eliminated after blood run. F5 is composed of the benefiting qi and hematinic, revealing the pathomechanisms are blood confusing, organs internal injuring and exogenous pathogens entering. F6 is composed of the tonification of liver and kidney and hematinic, revealing that when to old age, cold wind and wet evil can pass into the human body because of liver and kidney deficiency. Blockading in the joints and forming arthralgia. In ancient times understanding the pathogenesis of the bi syndrome of joint, It is importance and universality that the wind, cold and wet these three kinds of evil in the Bi Syndrome pathogenic. The drug therapy and prescription drugs mainly use warming medicine, relieving medicine, resolving dampness medicine and tonic medicines in ancient times.2. Differential treatment2.1 Internal treatmentQu Xie include expelling wind, clearing away cold, dehumidification and reducing fever. Tong Luo include activating blood and expectorating. Righting include strengthening the spleen-stomach and tonifying liver and kidney.2.2 External treatmentExternal treatment methods include acupuncture, moxibustion, point method, dry method, fixing method, paint rub method, application methods, etc.2.3Mix treatmentInternal treatment and external treatment were using together.Conclusion:The study found the development and evolution about recipe treatment of the bi syndrome of joint past dynasties. Reasoning out differential treatment rules of knee osteoarthritis with TCM by the summary of law of the bi syndrome. Identification include 5th types about Cold-damp invasion, Qi stagnation and blood stasis, Stagnation of qi and phlegm coagulation, Insufficient liver and kidney and Righteousness deficiency. The ancient used the treatment methods of osteoarthritis with righting, reducing fever, relieving, dampness, activating blood, Qi, warming, rheumatism and expectorating. Including Qu Xie, Tong Luo and Righting are the main treatment of osteoarthritis, emphasising on the application of righting therapeutic method. External treatment methods include acupuncture, moxibustion, point method, dry method, fixing method, paint rub method, application methods, etc.