The Correlation Of 25-Dihydroxyvitamin D And The Quality Of Life Of The Elderly

Objective: Our specific aim was to determine whether serum 25-hydroxyvitamin D level was associated with the state of health and quality of life of the middle-aged person and the aged.Methods:We measured 25-hydroxyvitamin D by ELISA and divided it into 3 groups: normal range(25OHD 75-120nmol/L)Vitamin D,Vitamin D insufficiency (25OHD 25～74nmol/L, and deficiency(25OHD<25nmol/L). We assessed the physical and mental health of the participants by the 36-Item Short-Form (SF-36) health survey.Results:1. Surveyed 25-hydroxyvitamin D levels of distributionThe normal range of vitamin D are 39,21.55% of the total number, the number of Vitamin D insufficiency are 109,60.22% of the total, and the deficiency are 33, 18.23% of the total number.The normal range of men are 24,28.92% of total number of males, Vitamin D insufficiency number of men 56.63% of the total number of males, and the Vitamin D deficiency number is 14.46%.The normal range of women are 15,15.31% of total number of females, Vitamin D insufficiency number of women 63.27% of the total number of females, and the Vitamin D deficiency number is 21.43%.Women in the vitamin D deficiency and inadequate rate of 84.69%, male 71.08%, the difference was statistically significant (P=0.03).2. The relation of 25-hydroxyvitamin D levels and SF-36 quality of life scores (1) Relation of 25-hydroxyvitamin D levels and SF-36 PCS scoresIt was significant deviation between the Vitamin D and the score of PCS,PF, RP, BP, GH (r=0.531 P=0.000, r=0.880 P=0.000,r=0.264 P=0.000,r=0.226 P=0.002, r=0.300 P=0.000).It was significant differences between the inadequate vitamin D group compared with the normal group, and the the lack of group with the normal in MCS, PF and GH (P<0.05). Lack of group significant difference compared with the insufficiency (P<0.05).It was significant differences between the inadequate vitamin D group compared with the normal group, and the the lack of group with the normal in RPand BP (P<0.05). Deficient group compared with the lack of difference was not statistically significant (P=0.243, P=0.187).(2) Relation of 25-hydroxyvitamin D levels and SF-36 MCS scoresIt was significant deviation between the Vitamin D and the score of MCS,RE, MH, VT, SF (r=0.347 P=0.000,r=0.273 P=0.000,r=0.228 P=0.000,r=0.189 P=0.011, r=0.205 P=0.006).It was significant differences between the inadequate vitamin D group compared with the normal group, and the the lack of group with the normal in PCS,MH and VT (P<0.05). Lack of group significant difference compared with the insufficiency (P<0.05).It was significant differences between the inadequate vitamin D group compared with the normal group, and the the lack of group with the normal in REand SF(P<0.05). Deficient group compared with the lack of difference was not statistically significant (P=0.085, P=0.078).3. Gender,age and education are not interfering factors (P>0.05).Conclusions:1. Prevalent in older age groups lack vitamin D, particularly important for women.2. the scores of MCS and PCS were positive associated with the 25-hydroxyvitamin D concentrations,and deficient group compared with the lack of RP,BP, REand SF was not statistically significant.3. Gender,age and education are not interfering factors.