Investigation Of Glycosylated Hemoglobin A1C Control And Its Influencing Factors In Type 2 Diabetic Patients

BackgroundDiabetes Mellitus(DM) is metabolic diseases characterized by chronic hyperglycemia. Type 2 Diabetes Mellitus(T2DM) patients account for 93.7% of all the DM patients in China. The monitoring of blood glucose is important for the diagnosis and treatment of DM. As the golden standard of evaluating blood glucose control, the present rate of good HbAlc control is generally low.ObjectiveThe study was aimed to evaluate HbAlc control and its influencing factors in T2DM patients, and analyze the association of HbAlc control with diabetic complications, providing theoretical basis for the prevention and treatment of T2DM.MethodsA cross-sectional study was carried out in 353 T2DM outpatients and inpatients from Shandong University Qilu Hospital. Questionnaire interview was used by trained surveyors to collect data on general characters, self-management, therapy, complications, blood glucose and HbAlc. The patients were divided into group A (HbAlc<6.5%) and group B(HbAlc≥6.5%). HbAlc was examined by high performance liquid chromatography. SPSS 13.0 was used for data analysis. Quantitative variables measured in this study were expressed as mean±SD and x2-test was used for categorical data. P<0.05 was considered statistically significant.Results①Group A accounted for 22.1%.②The prevalence rates of cerebrovascular diseases and diabetic retinopathy were significantly higher in group B than in group A(P<0.001,P=0.008, respectively).③The rates of blood glucose examining(≥4 times per month) and HbAlc examining(≥3 times per year) were 39.3% and 10.8% respectively, and only 5.8% of the patients accepted the above two mentioned examinings. The rates of patients who were knowledgeable on DM, controlled diet and took regular exercises were 35.4%,31.4% and 53.1%, respectively.ConclusionsThe present rate of good HbAlc control was low in T2DM patients, which can be associated with the occurrence of diabetic complications. The current situation of self-management is not satisfying, so it is necessary to take more rigorous individual diabetic health education to improve HbAlc control, especially in the management of monitoring on blood glucose, examining HbAlc, diet control and regular exercises.