Ultrasound Detect The Endothelium-dependent Vasodilatation In Fatty Liver Patients Of Young And Middle-aged

Objective1.Under the condition of patients with fatty, brachial artery pressure to observation the diameter changes, to realize the humerus artery endothelial dependence;2.FMD technology early diagnosis of clinical application value in diastolic function changes in fatty.Methods1.To select 69 case, all the participants on the physical examination, by CDFI ultrasound and test results are divided into three groups:fatty liver 20 team (â… ),fatty liver with high blood-fat 24 team (â…¡) and healthy control group 25 (â…¢)2.To observe brachial artery dynamically, measure its inside diameter, by FMD detection technology witch underlaying echo-tracking(ET) without wound,before and after reactive hyperemia(RH). Calculate the Flow-mediated dilation (FMD) induced by RH, Its computation formula (FMD)= [(reactive hyperemia brachial inner foundation-after the brachial artery diameter)/state based state brachial diameter] by 100%,to reflect its vasodilation function.Results1.Three groups of research objects and experiment result difference was NSS Not statistically significant (P> 0.05). Fatty liver group and control group (TC, TG, LDL-C, HDL-C) difference was NSS Not statistically significant (P> 0.05), with high lipid group (TC, TG. LDL-C. HDL-C) was obviously higher than the other two groups (P< 0.01).2.Three basic research object brachial diameter difference was NSS Not statistically significant (P> 0.05). The FMD in patients(â… )group and (â…¡)group was significantly less than in healthy subjects (â…¢) (P<0.01); While in patients (â…¡) group it was obviously lower than that in patients (â… ) group (P<0.05). Conclusion1.In patients with fatty liver the endothelium-dependent vasodilatation is impaired;2. Vasodilation function influenced by high blood-fat in a large extent;3. FMD can evaluate vasodilation function early and objectively.