Retrospective Analysis Of The Effect Of Alimentary Tract Bypass And Non-bypass Reconstruction On Type 2 Diabetes Mellitus: A Report Of 57 Cases

Objectives:To study the effect of alimentary tract bypass and non-bypass reconstruction on type 2 diabetes mellitus (DM).Method:Data of 57 operative cases with MD in general surgical department of the Second Affiliated Hospital of Dalian Medical University were analyzed retrospectively, who had been cured by surgical treatment with control, alimentary tract bypass and non-bypass reconstruction group from 2001 to 2008 because of benign and malignant lesions in their stomach. All cases are divided into control group, alimentary tract bypass and non-bypass reconstruction group. Data of blood glucose between the three surgical treatments are compared in each time point.Result:There are no significant difference in the sex, age, DM history, the number of operation cases, follow-up and the composition of diagnose among control, alimentary tract bypass and non-bypass reconstruction groups. In the group of alimentary tract bypass reconstruction,25 patients are followed up,3 patients are inefficient,9 are improved, and 13 are cured, the remission rate is 88.00%,the longest follow-up time is eight years, the shortest follow-up time is two years. In the group of alimentary tract non-bypass reconstruction,13 patients are followed up,10 patients are inefficient,3 are improved, the remission rate is 18.75%, efficacy and the remission rate are all significantly higher in alimentary tract bypass reconstruction when they are compared with alimentary tract non-bypass reconstruction. The body height data of 12 patients are known,1 patient is inefficient,8 are improved,3 are cured, the remission rate is 91.67%; In follow-up periods,2 hours'postprandial blood glucose of the followed-up patients in alimentary tract bypass reconstruction is significant lower than normalvalue (11.1mmol/L); In follow-up periods, morning fasting blood glucose in alimentary tract bypass reconstruction is significant lower than that of preoperation; After alimentary tract bypass reconstruction, morning fasting blood glucose in the second week is significant lower than that in the first week,2 hours'postprandial blood glucose of the second week is no significant lower than that in the first week.Conclusion:Alimentary tract bypass reconstruction can make an active affection on type 2 diabetes mellitus patients; alimentary tract bypass reconstruction can control the blood glucose of type 2 diabetes mellitus patients with Body Mass Index (BMI)>35 probably; the therapy action of alimentary tract bypass reconstruction on type 2 diabetes mellitus patients perhaps begins from the second week post-operatively.