Primary Research Of Real-time Ultrasound Angiography In Imaging Of Cerebral Arteries And Diagnosis Of Cerebral Artery Occlusion

Objective:1.To evaluate the effectiveness of transcranial ultrasound angiography that offers an angiography-like view of the intracranial arteries in healthy people.2.To evaluate diagnostic value of transcranial ultrasound angiography on the cerebral arterial occlusion from comparing with DSA or MRA.Methods:The study included two groups. Group 1 included 25 healthy volunteers. There were 15 men and 10 women (age range,37-68 years; mean age,53±14 years). Group 2 included 22 patients who were suspected with cerebral arterial occlusion from 2009.4 to 2010.1. There were 14 men and 8 women (age range,40-76 years; mean age,59±13 years). Group 1 accepted the transcranial ultrasound angiography and head MRA scan in one week. Group 2 accepted the transcranial ultrasound angiography and head DSA or MRA scan in one week. We observed the cerebral arteries of the group 1 after ultrasound scan, including segments of the middle cerebral artery (M1, M2 and M3), the anterior cerebral artery (A1 and A2), the posterior cerebral artery (P1, P2 and P3) and the internal carotid artery (Cl/2 and C3/4). All the results from transcanial ultrasound angiography were compared with MRA, and investigated the effectiveness of transcranial ultrasound angiography on the displaying the cerebral arteries in healthy people. We observed group 2 whether there was a cerebral arterial occlusion. And the results were compared with DSA or MRA, and investigated the value of transcranial ultrasound angiography on the diagnosis of the cerebral arterial occlusion.Result:Only 1 people from group 1 couldn't achieve the cerebral arteries image because of inadequate transtemporal acoustic window. The image of ipsilateral cerebral arteries and entire circle of Willis of the other 24 people could be achieved by transcranial ultrasound angiography. All the members of group 1 displayed all the cerebral arteries after MRA scan. In all the members of group 2, the image of cerebral arteries and Willis circle could be achieved. We observed the cerebral arteries of including ACA, MCA, and PCA. We found 14 arteries occlusion by transcranial ultrasound angiography, including 11 MCA and 3 ACA occlusions. Thirteen arterial occlusions were confirmed by DSA or MRA, including 11 MCA and 1 ACA occlusion.Conclusion:1. Transcranial ultrasound angiography had a high rate in imaging cerebral arteries.2. Transcranial ultrasound angiography provides high sensitivity and high specificity in diagnosis of cerebral arterial occlusion.