Effect Of Microsurgical Treatment For Intracranial Aneurysms

Objective:To discuss the clinical effects of microsurgery in treating cerebral aneurysms.Methods:A series of 187 patients with intracranial aneurysm who were treated surgically in our department were analyzed retrospectively, 101 patients of which were follow-up visit for 6 month to 40 months, in average 21 months. Hunt-Hess grade,CT Fisher grade,location and size of aneurysms,age and timing of operation that might affect the clinical effects of microsurgery and incidence rate of hydrocephalus were analyzed. The mRS of discharge and the corresponding mRS of follow-up visit were all analyzed.Results:Hunt-Hess grade,CT Fisher grade and age are positively related to mRS, patients with higher Hunt-Hess grade, higher CT Fisher grade and older age may have worse clinical effects(P<0.05); Timing of operation is negatively related to mRS of hospital discharge (P<0.05), while timing of operation is not related to mRS of follow-up (P> 0.05); size and location of aneurysms are not related to mRS(P>0.05). Patients with hydrocephalus have higher Hunt-Hess grade, higher CT Fisher grade and older age than those without hydrocephalus(P<0.05). Patients whose mRS were 1,2,3 or 4 While discharged would have better long-term effects (P<0.05), but Patients whose mRS were 5 While discharged would have worse long-term effects (P>0.05).Conclusion:The clinical effects of microsurgery for cerebral aneurysms can be remarkably affected by Hunt-Hess grade, CT Fisher grade and age of patients; The short-term effect of early microsurgical treatment for intracranial aneurysms is better than the medium-term and late microsurgical treatment, but there are no Obvious differences between the long-term effect of early, medium-term and late microsurgical treatment. Higher Hunt-Hess grade, higher CT Fisher grade and older are all risk factors for hydrocephalus; Patients whose mRS were 1,2,3 or 4 While discharged would have better long-term effects.