Skin Nodules As The First Symptom Of Sarcoidosis: A Case Report And Review Of The Literature

Objective: To improve performance on the skin as the first symptom of sarcoidosis. Patients and methods: One cases of nodular skin biopsy diagnosed as sarcoidosis in patients with an analysis of clinical data, Search the database of Chinese scientific and technical journals in 1989 published so far included 77 cases of damage to the skin as the first symptom of the reported cases of sarcoidosis, Information on 25 cases in which a more comprehensive analysis of cases and in conjunction with relevant literature review. Result: Sarcoidosis is a systemic disease of unknown cause which has noncaseating granulomas in biopsies as histologic demonstration. The cause and pathogenesis remain unknown. women are more frequently affected than men. onset of disease is usually in the twice to fourth decade. sarcoidosis symptoms can reffer to subtotal organs. course of diseases contain acute,subacute and chronicity. sarcoidosis is characterized in about 90% of patients by gramulomatous inflammation of the lung. Skin lesions accounted for 20-35%, skin lesions as the first symptom in patients is rare. The performance of their skin lesions is Virous, skin lesions could be duplication between them, Easily be mistaken for other skin disease. There is a long time from outburst to diagnosis,2 months to 40 years, The average diagnosis time is 45.4 months. When Combined damage to other systems(More damage to the lungs), Sarcoidosis was suspected,all patients were misdiagnosed in Varying degrees. There is no special treatment for the cause of the disease, multi-system damage in patients with severe should be given clinical interventions actively, Sarcoidosis was positive tendency, However, in the course of treatment should pay attention to follow-up. Conclusion: Skin lesions as the first symptom of sarcoidosis is easily mistaken for other skin disease. because of their diversity of Skin damage, sometimes it is difficult to diagnose rely on skin lesion morphology alone. histological biopsy of sarcoidosis is indispensable,so we should be doing everything possible to obtain histological evidence in clinical practice, Skin biopsy is safe, convenient and accurate, Therefore, patients can not rule out the diagnosis of sarcoidosis who have skin damage should line a clear diagnosis of the skin biopsy as soon as possible.