The Analysis Of 1020 Cigarette Smokers Pulmonary Function Examination

Objectives: The aim of this study are to emphasize the importance of complicating chronic obstructive pulmonary disease for the clinician through performing Spirometry examinations in cigarette smokers who are outpatient visits or health examination or surgical procedures in which newly diagnosed chronic obstructive pulmonary disease(COPD).Methods: In Dalian medical university affiliated the second hospital pulmonary function laboratory date from August 1, 2006 to December 31, 2008, 1020 patients were eligible to be included in the analysis. To be included, patients must have been over 40 years of age at their initial visit have received a COPD, Then detail record the presence of a chronic cough, sputum production ,or shortness of breath. ,Tobacco smoke history or smoking cessation , Whether or not a family history of COPD ,measure weight and height .According《the diagnosis and management of chronic obstructive pulmonary disease guidelines ( 2007 Revised edition )》diagnostic standard , a post-bronchodilator forced expiratory volume in one second (FEV1)/forced vital capacity (FVC)<0.7 confirms the presence of airflow limitation that is not fully reversible, excluding other cardio- vascular and pulmonary disease,Then diagnosis COPD.. the results of the smoking questionnaires, and the spirometric measurements were entered into the database created for the research work, and were analyzed using a SPSS11.5 statistical software package. Descriptive statistics were cal- culated using the mean±SD. Pearson coefficients were prepared. Statistical significance was considered to be present at p<0.05. A multivariate logistic regression analysis was performed to investigate the relationship of different variables with the sustained cessation rate. Results: In 1020 patients,76 patients were diagnosed COPD , mean age(62.5±8.83) years ,mean age of start smoking(22±3.76)years, mean smoking history(39.01±7.37)years,mean smoking index(43.25±8.25) pack-years ,the prevalence of stage I (mild), stage II (moderate), stage III (severe), and stageIV (very severe) COPD was0.49%, 3.24%, 1.96%, and 1.76%, respectively. There were correlations in FEV1/FVC with age of start smoking, daily consumption, smoking history and smoking index ( P< 0.05).There were negative correlations between FEV1%pre and everyday consumption or smoking history, And a positive correlation between FEV1%pre and age of start smoking. There were negative correlations in FEV1,FEV1%pre,FEV1/FVC% with sputum and dyspnea, I.e, The more worsen pulmonary function, the more sputum and dyspnea getting worse.Conclusion: COPD patients are designed with Spirometry ex- aminations in smokers with symptoms , their worsen pulmonary function are concerned with age of start smoking and smoking index, Smokers should think highly of pulmonary function examination.