The Protective Effects Of Tongxinluo Capsule On Myocardium After Reperfusion In Patients With Acute Myocardial Infarction

Objective: To investigate the protective effects of Tongxinluo capsule on myocardium after reperfusion in patients with acute myocardial infarction.Methods: This research uses stochastically, the comparison clinical trial method, the electricity group hospital heart center line of acute cardiac arrest PCI surgery patient example has carried on the observation to May, 2007 to October, 2008, divides into the treatment group (Tongxinluo capsule + western routing) and the control group (western routing only), separately and treats the latter 90 day of intentionally function appraisal, Chinese medicine clinical symptoms grading, Left Ventricular End-diastolic Diameter (LVEDD), the left ventricle contraction last stage inside diameter (LVESD), the main cardiovascular event formation rate and so on, obtained data feeds the computer, carries on the statistical analysis using the SPSS11.0 software.Results: Through the Chinese medicine clinical symptoms quantification grading comparison, treatment group's total effectiveness is 97%, control group total effectiveness 85%, the treatment group curative effect surpasses the control group; Treatment first and last groups LVEF, Left Ventricular End-diastolic Diameter (LVEDD), Left Ventricular End-Systolic Diameter (LVESD), the main cardiovascular event formation rate, the heart function grade the NYHA situation, ST-segment resolution to lead four aspects to have the varying degree improvement (P<0.01 or P<0.05),The difference has statistics significance.Conclusion: Tongxinluo capsule involves the technique after the acute cardiac arrest the patient symptom improvement to have the explicit function. After being hollow winds the capsule may improve the PCI involvement technique, patient's cardiac muscle microcycle irrigation; Tongxinluo capsule to be possible to change the benevolence function situation; Tongxinluo capsule to be possible to improve the ventricle to remould; Tongxinluo capsule to be possible to reduce the main cardiovascular event formation rate, can improve the PCI involvement technique patient's quality of life, the improvement prognosis, thus obtains Tongxinluo capsule to be able to improve the crown arteries microcycle, realizes the cardiac muscle effectively to pour into again.