The Clinical Evaluation Of Two Method To Detect The Airway Reactivity In Children With Asthma

In search of childhood asthma:A comparison Of hypertonic saline and exercise bronchial challenge tests and clinical evaluationObjectsBronchial asthma(asthma) is known as one of the respiratory infectious diseases found mainly in children.The incidence of asthma in children has gone up year by year. Bronchial hyperreactivity(BHR) is a characteristic feature of asthma and develop important factor.Recent years,asthmatic clinical situation is multiplicity.Some even is not typical example,in the all country epidemic investigation of 2000 year, childhood asthma diagnose accordance rate is 63.62%.Cough variability asthma(CVA) diagnose accordance rate is only 31.5%.To explain,diagnosis level of asthma must be elevated.Being near year progress,bronchial challenge tests will be consummate and include direct provocation test and indirect provocation test.Of the total,indirect provocation is an original and special provocation in childhood asthma.Various kinds of provocation had been deeply investigated in specific method,characteristic, evaluation index and clinical application value.During the clinical research,the purpose of the present study was to examine the utility of the different challenge tests in childhood asthma.We therefore compared exercise and hypertonic saline challenges and retrieval a kind of convenient,digestible challenges in childhood asthma.At present,there have been various kinds of comparative challenges clinical reports in abroad.But in domestic no have.Therefore,during this experiment we will compare with exercise and hypertonic saline challenges in clinical to discovery the empirical method that refer to children and clinical evaluation.Methods Thirty-four patients associated with childhood asthma and chronic cough were selected.Diagnostic criteria based on prevention and cure rule of children bronchial asthma that is revise edition.The same patients will be examining the utility of the exercise challenge tests and hypertonic saline challenge tests.The same patients are control group by self to wipe out individual variation.Results1.The same patient of childhood asthma compares with exercise and hypertonic saline challenge tests,the result has statistical significance.(P＜0.01)2.the five patients be suspected CVA have been carried out hypertonic saline and exercise challenge tests,among 2 examples are masculine in hypertonic saline challenge test,the same time,are negative in exercise challenge test.3.The 4 examples of normalization treatment period have been carried out two kinds of challenge tests in different period of course of disease,the course of treatment the more short,the airway reactivity(AR) the more high,vice versa. Among the totle,the masculine of hypertonic saline is super to exercise challenge.Conclusion1.The same patient of childhood asthma compares with exercise and hypertonic saline challenge tests,the masculine of hypertonic saline is super to exercise challenge.2.Hypertonic saline and exercise challenge are all masculine of the acute stage patients in children asthma.3.To diagnose CVA,the sensitivity of hypertonic saline is super to exercise challenge.