| PurposeDitan Yishen Quyu observed treatment of vascular dementia (Vascular Dementia,VD) Clinical efficacy and safety to Western medicine for the control Hydergine tablets for a wide range of clinical applications at providing a scientific basis.Data and Methods1.WHO used this subject published by the spirit of the United States Academy of Neurology Vascular dementia diagnostic criteria (DSM-â…£),combined with mini-mental state examination(MMSE), activities of daily living scale(Activity of daily living,ADD, clinical dementia rating table(Clinical dementia rating,CDR) by the patients agreed to comply with the standard case,and included in the study of 60 cases,according to the order of treatment is divided into 40 cases of treatment group and 20 cases of the control group.2.Treatment group to Yishen Ditan Quyu law(by gastrodin, Earthworm,Wong Jing,Acorus gramineus,Ligustrum lucidum,leech drug component),made of pills,oral 6 each,3 times daily, continuous use 8 weeks,1 month follow-up times;the control group Hydergine tablets oral 2 each,3 times a day medication for 8 weeks, 1 month follow-up times.3.Treatment group and control group patients before and after treatment in cognitive function,the relevant points of Chinese medicine and changes in symptoms,medication use before and after the monthly record of time,fill out the clinical observation of periodic table.4.One course of medication before and after the record of the general physical examination items(that is,body temperature, respiration,pulse,blood pressure),blood,urine,fecal conventional,heart,liver and kidney.functions,blood rheology, electrocardiogram,to safety observation.5.Statistical treatment:measurement data using t test,x2 test the use of count data,the use of Level Ridit analysis of data.Results1.the two groups after treatment MMSE score,ADL score and the points syndrome improved compared with before treatment(P <0.01) differences were significant,indicating that Ditan Yishen Quyu law has significantly improved in patients with vascular dementia intelligence,the role of activities of daily living.Comparison between the two groups(P <0.05) differences are also significant, indicating that Ditan Yishen Quyu vascular dementia treatment more effective than Western medicine in Xide town.Medication process, no significant adverse reactions,safety,good.2.Related to the total symptom score compared Traditional Chinese Medicine:the treatment group after treatment compared with before treatment there is a very significant difference(P <0.01), the control group after treatment compared with before treatment there is significant difference(P <0.05),one course after the end of the two groups Chinese medicine symptom total score were significantly difference(P <0.05),the treatment group was significantly less than the control group.3.Safety analysis:two groups of patients during the medication, no adverse reactions occur,medication before and after no significant changes in vital signs,medication before and after the treatment and control groups of blood,urine,feces of conventional, heart,liver,kidney function and no significant changes in ECG. Show that the refined world of pills in the treatment of vascular dementia(VD) process no significant side effects,safe and reliable.ConclusionThrough the efficacy and safety of the above analysis shows that treatment of Quyu Ditan Yishen vascular dementia(VD) of the exact clinical efficacy is superior to western medicine tablets Hydergine can improve cognitive abilities in patients with Chinese medicine and related symptoms,safe and reliable can improve the quality of life of patients for the treatment of vascular dementia and one of the ways to effective drugs,it is applied. |
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