Study On Epidemiology Of Bacteremia In Intensive Care Unit In The First Affiliated Hospital Of Zhejiang University

ObjectiveTo study the epidemiology and the sensitivity for antibiotics of bacteremia in intensive care unit,and provide the reference for the clinical antimicrobial agents usage.MethodsIn this paper 465cases of bacteremia from Jan.2005 to Dec.2007 in the First Affiliated Hospital,Medical College of Zhejiang University were retrospectively analysec.Results1465 strains of pathogens were isolated in three years,and positive rates were 22.6%.155 strains were fungis(10.6%),611 strains were gram-positive bacteria(57.9%),392 strains were gram-negative bacteria(37.1%).G+ strains mainly included coagulase-negative staphylococcus(CNS 43.0%);Staphylococcus aureus(2.1%);the sensitivity antibiotics were vancomycin and teicoplanin.G- strains mainly included Acinetobacter baumanii(8.6%);Stenotrophomonas maltophilia(6.6%); Pseudomonas(5.1%);Klebsiella pneumonia(5.3%),the sensitivity antibiotics was cefoperazonel/sulbactum.ConclusionsThe positive rates of Blood culture was higer in intensive care unit than in others. We should pay more attention to coagulase-negative Staphylococcus for its high infection rate.The sensitivity antibiotics to G+ were vancomycin,teicoplanin.The sensitivity antibiotics to G- was cefoperazonel/sulbactum.Antimicrobial therapy should be conducted according to susceptibility test.The candidemia caused by NAC increased in recent 3 years.