Study On Seroprevalence Of Toxical Helicobacter Pylori Infection In Young Military Officers And Soldiers

Background and Objective:As a bacterium with high infectious rate in the worldwide,H.pylori represents extremely severity in the developing countries.It is now known thatH.pylori is closely associated with chronic gastritis,peptic ulcer and gastric MALT lymphoma.Besides,H.pylori is also the potential etiological factor of gastric carcinoma.Numerous epidemiological studies reveal that many factors influence the crowd infection rate of H.pylori.It is generally acknowledged that there are three transmission pathways:oral-oral,fecal-oral and gastric-gastric routes.In the developed countries,the main transmission pathway is oral-oral,while in the developing countries it is fecal-oral route.These three transmission routes all exist in our country.In view of Group living as the main life style in the forces,the living conditions of the forces may contribute to the spread of H.pylori.In this study,to find out the differences of H.pylori infection between recruits and veterans and the influence of group living on H.pylori infection,we detect the CagA-H.pylori-IgG antibodies in serum of recruits and veterans by ELISA method,and analyse the potential risk factors of H.pylori infection in recruits.Materials and Methods:389 male recruits and 312 male veterans were collected from Beijing military district in the period of 2008 to 2009.389 recruits answered the designed questionnaire.Blood samples were collected from 389 male recruits and 312 male veterans.The serum samples were tested for the presence of H.pylori IgG antibodies using CagA-H.pylori-IgG kits,and then assess H.pylori infection of these samples.Results:H.pylori prevalence of recruits was 54.76%.In Logistic analysis,there was a statistical trend to associate group living,keeping of pets and poultry,drinking water,suffering from H.pylori infection or peptic ulcer or gastric cancer in family members(p＜0.05) to H.pylori infection.The H.pylori prevalence was 86.22%in 312 soldiers who joined the army at least for 3 years and there were significant differences between recruits and veterans(p＜0.001).According to group living time,the recruits were devided into 3 groups,i.e.no group living,group living in 3 years and group living more than 3 years.In univariate analysis,there were significant differences between the third group and the other two groups(p＜0.05), while there were no differences between the first group and the second group.312 veterans were devided into 3 groups by their military service,i.e.3～5 years,6～8 years and 9 years and above.There were no differences among these groups.Conclusions:1.The infection rate of H.pylori in recruits is similar to the general population. There was a trend to associate group living,keeping of pets and poultry,drinking water,suffering from H.pylori infectiong or peptic ulser or gastric cancer in family members to H.pylori infection.2.There are significant differences between recruits and veterans,which may result from group living condition in the forces.3.The H.pylori infection rate of military officers and soldiers are in a high state. Some measures should be adopted,such as improving living conditions, developing health education and so on,in order to decline the H.pylori infection rate.4.The H.pylori infection rate was stable in soldiers servicing at least for 3 years in the forces.