The Clinical Value Of ^99mTc-DTPA Renography In Evaluating Function Of Non-visualized Kidney In Intravenous Pyelography

Objective:To analyze the clinical value of ^99mTc-DTPA renography in assessing function of non-visualized kidneys in intravenous pyelography(IVP).Methods:80 patients with non-visualized kidney in IVP were carried out ^99mTc-DTPA renography in our department from 2005 to 2007,to analyze the results combined with the patients' clinical data.Result:Among total of 80 cases with non-visualized kidney in IVP,renal parenchyma of 37 cases were non-visualized under ^99mTc-DTPA renography,GFR was 0 ml/min,32 cases carried out nephrectomy;Renal parenchyma of the rest 43 cases were visualized under ^99mTc-DTPA renography,GFR were(20.03±9.64) ml/L,among them 9 cases were carried out nephrectomy, 34 cases received kidney-sparing operation;The 34 cases(divided into 4 groups according to range of GFR) recheck ^99mTc-DTPA renography 2 months later after the operation,Preoperative GFR within(1～10) ml/min,GFR were(4.25±2.99) ml/min,postoperative GFR were(4.00±2.94) ml/min,t=0.522,P＞0.05,indicated no significant change of GFR after the operation; Preoperative GFR within(11～20) ml/min,(21～30) ml/min,(31～40) ml/min groups, preoperative GFR were(15.38±2.63) ml/min,(24.83±2.92) ml/min,(34.25±2.75) ml/min, postoperative GFR were(17.77±3.79) ml/min,(29.42±3.90) ml/min,(40.25±3.50) ml/min respectively,paired t-test,P＜0.05,indicated that 2 months' postoperative GFR increased significantly,the function of kidneys recovered in some degree.Conclusion:1.Among the kidneys non-visualized in IVP which were considered "functionless" in the past,some remain partial function in ^99mTc-DTPA renography;Superior to IVP,⁹⁹Tc^m-DTPA renography is an accurate,sensitive and reliable method;2.AS an ideal method to evaluate kidney function,especially for the individual kidney, ^99mTc-DTPA renography could accurately analyst the preoperative individual kidney function and postoperative recovery for IVP non-visualize kidneys,It was useful in directing the selection of operation methods and providing objective proof of making correct decision on weather preserved the defected kidney or not.