Clinical Analysis On 166 Cases Of ARDSp & ARDSexp

Objective to compare the clinical differences between ARDSp & ARDSexp.Methods Clinical data of patients with ARDS in intensive care units in our hospital from February 2003 to February 2008 were collected, and they were divided into pulmonary (ARDSp) and extra-pulmonary (ARDSexp) groups according to the inducing factors.Results there were 99 cases with ARDSp and 67 cases with ARDSexp including male/female 67/32 and 38/29,age (47.19±17.22) and (45.79±17.91) years old, respectively .There were no significant differences between the two groups on the following items as age,gender ,APACHE (acute physiology and chronic health evaluation) III score, Q_S/Q_T,time of ventilation support,time of treatment in ICU (P > 0.05). The oxygenation of ARDSexp was improved more significant than ARDSp by ventilation support. The mortality rate was higher in ARDSp group than that in ARDSexp (P=0.025) .Major primary disease for ARDSp was severe pneumonia,for ARDSexp were sepsis, severe acute pancreatitis.The incidence rate of MODS (multiple organ dysfunction syndrome) was higher in ARDSexp than that in ARDSp.MODS was the major lethal cause. The use of Corticosteroids was not helpful to reduce the mortality rate of ARDS.Conclusion The mortality rate of ARDS is high. There are differences between ARDSp and ARDSexp in mechanical ventilation effect and mortality rate; MODS is the major lethal cause; The use of Corticosteroids is not helpful to reduce the mortality rate of ARDS.