A Clinical Study Of Pulsed Electromagnetic Fields Effects On Aged Female With Primary Osteoporosis

Objective: To observe the therapeutic effects of pulsed electromagnetic fields (PEMFs) on aged female with primary osteoporosis.Methods: Thirty-six aged female patients with primary osteoporosis received PEMFs therapy, 20 minutes per day, once a day for 30 days, and received supplemental calcium (500 mg/d) and vitamin D (800 IU/d). Pain score was recorded by numerical rating scale (NRS), the concentration of serum osteocalcin (OC) and serum C-telopeptide of type I collagen (CTX-1) were dividedly detected by radioimmunoassay (RIA) and by enzyme linked immunosorbent assay (ELISA). in addition, the bone mineral density (BMD) were evaluated by Dual Energy X-ray Absorptiometry (DXA). All the indexes above were recorded before and after theatment.Results: It was statistical significance that the value of Numerical Rating Scale (NRS) degraded (P<0.05). No augment of the serum osteocalcin (OC) level statistically before and after treatment (P>0.05). Serum C-telopeptide of type I collagen (CTX-1) degraded (P<0.05) after treatment, moreover further degraded (P<0.05) 3 months later. Re-examination of Bone Mineral Density (BMD) showed that the average BMD increased 0.021 g/cm2 (P<0.05) in Wards triangle region significantly, though there was no statistical significance in increasing of BMD in femur neck (P>0.05) and in trochanter major (P>0.05).Conclusion: Pulsed electromagnetic fields (PEMFs) can ameliorate pain, and increase BMD, and the major mechanism may be inhibiting bone resorption in aged female patients with primary osteoporosis and continue these effects after therapy few months after treatment.