Clinical Research Of The Relationship Between The Syndrome Differentiation And Blood Fat In Type 2 Diabetes Mellitus Combined With Coronary Heart Disease And Its Risk Factors Analysis

Objective:To discuss the relationship between the syndrome differentiation and blood fat level in type 2 diabetes mellitus(T2DM)combined with coronary heart disease(CHD) and to investigate its risk factors.Methods:Three hundred and thirty patients diagnosed as T2DM,were divided into two groups,one group pure T2DM which consisted of 161 patients and the other group T2DM with CHD which consisted of 159 patients.We divided the 159 patients with coronary heart disease into four different groups as deficiency of qi and yin,phlegm syndrome,blood stasis syndrome,and yang deficiency of heart and kidney with method of syndrome differentiation, and then observe their blood fat level.Data of gender,age,duration,hypertension,body mass index(BMI),fasting plasma glucose(FBG),2h plasma glucose(P2BG),glycosylated hemoglobin Alc(HbAlC),total cholesterol(TC),triglyceride(TG),high-density lipoprotein-chole sterol(HDL-C),low-density,lipoprotein cholesterol(LDL-C),apolipoprotein A(ApoA),apolipoprotein B(ApoB),fibrinogen(FIB),and microalbuminuria(MAU)in the two groups were compared and analyzed.The Logistic regression analysis was used among 320 patients with type 2 DM.Results:①159 patients of T2DM with CHD consist of 58 of phlegm syndrome (account for 36.5%),44 of deficiency of qi and yin(account for 27.7%),29 of blood stasis syndrome(account for 18.2%),and yang deficiency of heart and kidney(account for 17.6%).②There were greater TC and TG in type of phlegm syndrome and type of blood stasis syndrome.There was statistic difference in TG between the type of phlegm syndrome and the other tree types(P＜0.05),and there were no statistic difference in TC,HDL-C, LDL-C and ApoA,in the four types of TCM.Compared to deficiency of qi and yin,there is statistic difference in ApoB,(P＜0.05).③There was a significant difference in age, duration,BMI,HbAlC,P2BG,TG,HDL-C,LDL-C,ApoA,FIB and MAU between group of T2DM and group of T2DM with CHD.(P＜0.05).There was no significant difference in FBG,TC and ApoB between two groups.(P＞0.05).Conclusion:There was close relation of phlegm syndrome,blood stasis syndrome, blood fat level and diabetic coronary heart disease.The risk factors in type 2 diabetes combined with coronary heart disease include age,duration,BMI,P2BG,TG,HDL-C, LDL-C,ApoA,FIB and MAU.Type 2 diabetes combined with coronary heart disease should be treated as early as possible.