Clinical Analysis Of Nosocomial Pulmonary Fungal Infection In Patients With Lung Cancer

Objective:To analyze and discuss the clinical feature and influence factor and get the message of fungal categorization of the nosocomial pulmonary fungal infection in patients with lung cancer of Xinjiang medical university affiliated Tumor hospital.To prevent and control the nosocomial infection.Methods:872 cases with lung cancer from 1Jan,2007 to 31 dec 2007 were retrospectively analyzed.,clinical records of 87 patients with nosocomial pulmonary fungal infection we analyzed the risk factors and fungal categorization.Results:In 872 patients with lung cancer with pulmonary fungal infection rate was 9.9%(87/872),71males and 16 females.The age was from 39 to81,with median age of 63.5.The candida accounted for 96.6%,aspergillus 2.3%and mold fungus 1.1%.candida albicans was major candida(81%).Other were candida slick(11.5%),candida krusei(7%),.The mian risk factor were age≥50 years,long-term hospitalization≥15天,cancer chemotherapy and radiaotherapy,invasive operation, leucopenia≥Ⅲgrade,application of antibiotic and homone(P＜0.05).Gender,lung cancer pathotype and operation had nothing to do with nosocomial pulmonary fungal infection in patients with lung cancer(P＞0.05).Conclusions:The effective method to reduce nosocomial pulmonary fungal infection in patient with cancer are reducing risk factors,early diagnosis,and early use of anti-fungus agents and adequate immunotherapy and supportive treatment.