Effect Of Cold Air Inhalation On Body Temperature And Hemodynamics In The Dog

Objective: To investigate the effect of cold air inhalation on body temperature, hemodynamic and blood-gas parameters in the dog.Methods: Eighteen healthy male dogs were randomly divided into two groups:hypothermia and normothermia.Dogs were anesthetized,and,a catheter was inserted into the right femoral artery.Next,a Swan-Ganz catheter was inserted into the pulmonary artery and the right ventricle through the right femoral vein, and then,connected with a multifunctional monitor.The animals were monitored for 2 hours while they were ventilated with cold air or room temperature air, and the body temperatures(Tnp,Tb,Ts), hemodynamc parameters(HR,SBP,DBP,MAP,CO,PAP,PCWP,CVP) and blood-gas parameters(PaO2,PaCO2,PH) were measured at 0min,30min,60min,90min,120min after mechanical ventilation.Results: There were no significant differences in all base values between hypothermic group and normothermic group(P > 0.05). Also, There were no significant differences in all values of body temperatures between these two groups(P>0.05);In addition, we found that there were statistical differences in PAP and PCWP at 30min,60min,90min,120min after ventilation between these two groups(P<0.05).The hypothermia dog had different values of HR and SBP in different time point. (P<0.05). There was statistical difference in PaO2 on 30min between the 2 groups(P<0.05).Futhermore, PaO2,PaCO2 and PH values were significantly different in different time point after ventilation in the hypothermia dogs(P<0.05).Conclusion: These results indicate that cold air inhalation has no effect on body temperature, although it influences hemodynamic and blood-gas values. Also, the hemodynamic and blood-gas values in hypothermia are still within the normal range.