Study On The Relationship Of Blood Components And Radiation Dose

Biodosimetry is method to evaluate dosage on a relationship between radiationquantities and effects by analysising the changes of quantity, concentration, activity and functionin bio-material after irradiation. Compared with physical dosimetry, biodosimetry isindividual-oriented and less influenced by lots of unpredicted factors, such as body movementsand ways of radiations etc. It has more advantages in rapid dosage scanning, quick triage, anddiagnosis on a large scale rescuing of individuals in accident. Results: At 24 hours afterirradiation with defferent doses, the level and activity of serum MMP-2 change markedly. At 24hours after exposure, there appeared some obviously different dots in low-molecular-weightprotein region. The expression of FcγRII, which mediated PBMC adhesion to IgG, declined by26.4%, 51.9% and 40.3% respectively in 2Gy, 4Gy and 6Gy groups at 6h after irradationcompared with no irradiation group(P<0.01). PBMC migration ability decreases 19.8%, 25.3%,44.9%respectivelyin2Gy,4Gyand6Gygroupsat6hafterirradiation. Alltogether,theseprimaryresultsarebeneficialreferenceonthefurtherresearchofbiodosimetry.