The Effect Of RMF(Rotating Magnetic Field) To The Inflamation Media In The Rat Prostatitis Model

【OBJECT】We take the research for the content changes of the inflammation media in the chronic prostatitis model caused by rotating magnetic field to treat of the mechanism of the affection of the rotating magnetic field to the chronic prostatitis and explore the new way to cure the chronic prostatitis.【METHOD】Choose 36 1-year old male SD Rats which weigh 500-800 gram and make the prostatitis models. After creating the prostatitis models following the Wei's way, we divide all of the rats into three groups on average randomly. They are control group which will never be therapied in any way, weak magnetic group which will be exposed in the 0.2T, 10±2 Hz rotating magnetic field for 30 min per day, intense magnetic group which will be exposed in the 0.3T, 10±2 Hz rotating magnetic field for 30 min per day. After 40 days therapy of the rotating magnetic field, we observe the inflammatory changes by the microscope and analysis the content changes of the (interlukin-6) and VEGF (vascular endothelial growth factor) in the prostate tissue of all the groups by the semi quantitative analysis of histochemistry.【RESULT】The inflammatory expression in the prostate tissue of the weak magnetic group is slighter than it is in the prostate tissue of the control team. The inflammatory expression in the prostate tissue of the intense magnetic group is slighter than it is in the weak magnetic group. The content of IL-6 (interlukin-6) in the prostate tissue of the weak magnetic group is less than it is in the prostate tissue of the control magnetic group remarkably and statistically ,p<0.05. The content of IL-6 (interlukin-6) in the prostate tissue of the intense magnetic group is less than it is in the prostate tissue of the weak magnetic group remarkably and statistically, p<0.05. The content of IL-6 (interlukin-6) in the prostate tissue of the intense magnetic group is less than it is in the prostate tissue of the control group remarkably and statistically ,p<0.05.The content of VEGF (vascular endothelial growth factor) in the prostate tissue of the weak magnetic group is less than it is in the prostate tissue of the control magnetic group remarkably and statistically,p< 0.05. The content of VEGF (vascular endothelial growth factor) in the prostate tissue of the intense magnetic group is less than it is in the prostate tissue of the weak magnetic group remarkably and statistically,p< 0.05. The content of VEGF (vascular endothelial growth factor) in the prostate tissue of the intense magnetic group is less than it is in the prostate tissue of the control group remarkably and statistically,p< 0.05. 【CONCLUSION】The rotating magnetic field affects the content of the inflammatory in the SD rat prostatitis model remarkably ,and relieves the inflammation in the prostate tissue. This points out the rotating magnetic field can be helpful to therapy the prostatitis to some degree.