The Pathology, Image And Clinical Research Of Ossifying Fibroma In Nasal Cavity And Paranasal Sinuses

Objective:To study the pathogeny,pathogenesis,epidemiology,symptom, sign,laboratory diagnosis,CT,pathology,clinic treatment,operation, subsequentness and prognosis of Ossifying fibroma in nasal cavity and paranasal sinusesMethods:reviewing the 8 cases of Ossifying fibroma in nasal cavity and paranasal sinuses which were dianosised and treated in First Affiliated Hospital of Guangxi Medical University from 1985 to 2007,referencing the articles about Ossifying fibroma in recent years,we have a analysis and summarization to Ossifying fibroma.4 typical cases are particularly reported.we also differentiate Ossifying fibroma to Fibrous dysplasia by CT and pathology.Discussion,the pathogeny of Ossifying fibroma in nasal cavity and paranasal sinuses is not clear yet.some hypotheses are popular—benign tumour from bone structure,trauma and heteroplasia,among the nasal sinuses, ethmoid sinus and sphenoid sinus are the easiest ones to be invaded by Ossifying fibroma.The typical signs of Ossifying fibroma in nasal cavity and paranasal sinuses are the indolence,progressing face tumefaction, exophthalmos and eyeball shift,other signs include the sniffles,nasal mucus, rhinorrhagia and headache.The clinical diagnosiss mainly depends on comparative imaging analysis and pathology.The main clinical differential diagnosis is Fibrous dysplasia.Ossifying fibroma showed an expansive well-defined lesions with calcium-like high density.The main imaging differential diagnosis between Ossifying fibroma and Fibrous dysplasia is their growth pattern,margin and size.Cementicle is the character of Ossifying fibroma in pathology.The main treatment of Ossifying fibroma in nasal cavity and paranasal sinuses is surgical operation.The operation methods include: nasal endoscopic management lateral rhinotomy,coronal incision, Caldwell-Luc'surgery,lateral rhinotomy with nasal endoscope,and image navigation in resection of the ossifying fibroma with nasal endoscope.The prognosis of ossifying fibroma is satisfying.Commonly,It will not recrudesce by a completely resection.Conclusion.Ossifying fibroma in nasal cavity and paranasal sinuses of the sinuses is a no-common disease in clinic.Most patients are teenagers.The typical signs are the indolence,progressing face tumefaction,exophthalmos and eyeball shift.The clinical diagnosiss mainly depends on comparative imaging analysis and pathology.The main treatment of Ossifying fibroma is surgical operation.The choice of surgical operations on was mainly decided by the location of ossifying fibroma,in the meanwhile,the organ function,the cosmetology,the surgical degree of difficulty,and the doctor's experience were taken into account.The prognosis of Ossifying fibroma in nasal cavity and paranasal sinuses is satisfying.Commonly,It will not recrudesce by a completely resection.