The Enzyme Histochemical Staining Of The Comitant Strabismus EOMs And The Expression Of Action And Myosin In These EOMs

Purpose: To investigate the structural difference of the extraocular muscles (EOMs) between the comitant strabismic patients and normal people, and to explore the possible mechanism of comitant strabismus.Methods: The histological difference of the extraocular muscles (EOMs) between the comitant strabismic patients and normal people were analyzed by immunocytochemistry with antibodies against actin and myosin, myofibrillar adenosine triphosphatase (mATPase).Results: The differences of myofibrils sum ratio between the comitant strabismic patients group and the normal group were no statistical significance(P>0.05) ,and expression of action and myosin between the comitant strabismic patients group and the normal group were statistical significance (P<0.01). No distribution advantage of muscle fiber type and muscle fibers type grouping phenomenon were observed.Conclusions: Myogenic changes occurred at the weakening EOMs of comitant stralismus ; The distribution of EOMs fibers and the expression of actin and myosin might play important roles in the mechanism of comtant strabismus; the change of fast and slow fibers ratio perhaps was not the reason for comitant Stralismus.