The Clinical Research On Primary Dysmenorrhea Treated By Moxibustion Therapy

Purpose: To observe the clinical curative effect and the influence ofprostaglandins f and serumβ-ep for the patients of the primary dysmenorrheaby the treatment of "qihuang" health promotion temperature moxibustion bag, andresearch the functional mechanism of it's effect from the angle ofneuroendocrine-immune network, it will provide some objective basis for thebettermen of moxibustion。Method: 62 cases of primary dysmenorrhea child-bearing period and unmarriedwomen(at the age of 20-30 years) were selected with certain diagnosticstandard. They were divided into two groups at random: Temperature-moxibustion-bag Group and Moxa-cone-moxibustion Group. Choose the mainacupoints:Zhongji(RN3),Guanyuan(RN4),Qihai(RN6)。Everytime we start therapyseven days of the menstruation coming, then to the menstruationg coming, everyday. Three-menses-cycle makes up an observing therapeutic course, measure eachindex before and after treatment respectively.The indexes are as follows:(1)Take out the blood of elbow vein, estimateβ-endorphin (β-cep) byradioimmunoassay(RIA) and prostaglandin F_2a (PGF_2a) by enzyme-linkedimmunosorbent assay (ELISA) before and after treatment. (2)Adopt the self-tableof the menstruation,to estimate the symptom of clinical pain before and aftertreatment.Result:(1) The total effective rate of treatment group was superior to that ofthe contrast group, but there is no statistically significant difference(P＞0.05).There is no remarkable difference on the relationship between effect and disease serous degree or the disease course (P＞0.05).(2) Before treatment, there is no statistically significant difference tothe level PGF_2a between the 2 groups. After treatment the level PGF_2a were lowerthan before treatment, but there is no statistically significant difference atthe decreasing rate (P＞0.05).(3) Before treatment, there is no statistically significant difference tothe levelβ-ep between the 2 groups. After treatment the levelβ-ep were higherthan before treatment, but there is no statistically significant difference atthe increasing rate。(P＞0.05)。Conclusion:(1) The result showed that Temperature-moxibustion-bag Group andMoxa-cone-moxibustion Group all cound reduce the clinical pain grade ofprimary dysmenorrhea patient, decrease PGF_2a contain and increaseβ-ep contain。So prove the Moxibustion treatment is one of the effective methods totreatprimary dysmenorrhea.(2) No obvious difference in treating primary dysmenorrhea was observedbetween Temperature-moxibustion-bag Group and Moxa-cone-moxibustion Group. Soprove these are the effective methods to treat primary dysmenorrhea. Moxibustionmust manipulate by doctor and is not convenient in operating, has the certainrisk. But Temperature- moxibustion-bag can not only avoid above-mentionedquestions but also manipulate by patients themselves and shorten the treatingtime to a certain extent. Therefore temperature-moxibustion-bag can replace withmoxa-cone-moxibustion to treat primary dysmenorrhea, it will provide someobjective basis for the betterment of moxibustion.(3)The effect of moxibustion can better modulate the secretion ofneuropeptide and prostaglandin, what is more, it can improve obviously thesymptom of clinical pains,physically and mentally healthly of primary dysmenoryand enchance the primary dysmenory women's quality of life. So we can deduce:The effect of moxibustion can improve the internal environment of primarydysmenorrhea patients by adjusting their neuroendocrine, thus reach the ideal result.